Gene detail

P4U35_RS12130

Histidine kinase, Classic

Bacillus mycoides · GCF_036211545

ClassHKTypeClassicLength458 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_036211545#P4U35_RS12130Stable P2CS identifier used across views.
GenomeGCF_036211545Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus
Selected clusterHKOC_1858247Run 6 · 48 sequences · id 100% · cov 80%
External referencesWP_002168206.1 · R8N3G0 · MIST4 P4U35_RS12130RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length458 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 458 aa (49.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa458 aa
HAMP: 165-232 aa (68 aa)1HisKA: 244-303 aa (60 aa)2HATPase_c: 349-448 aa (100 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
165-232 aa · 68 aa · 14.8% of protein
Raw tokenHAMP:165:0.0000000000000026:232:68:69
2 HisKA#2
244-303 aa · 60 aa · 13.1% of protein
Raw tokenHisKA:244:0.00000000000147:303:61:64
3 HATPase_c#3
349-448 aa · 100 aa · 21.8% of protein
Raw tokenHATPase_c:349:2.84e-17:448:103:109
  • Raw architecture: HAMP:165:0.0000000000000026:232:68:69#HisKA:244:0.00000000000147:303:61:64#HATPase_c:349:2.84e-17:448:103:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_036211545::NZ_JARMBU010000009.1::G00041
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span263106-265122Genomic interval covered by the local TCS group.
Identifiers
Old locus tagP4U35_12095RefSeq proteinWP_002168206.1
Context group IDGCF_036211545::NZ_JARMBU010000009.1::G00041
Context members
P4U35_RS12125P4U35_RS12130
Partner locus tags
P4U35_RS12125P4U35_RS12130
Partner old locus tags
P4U35_12090P4U35_12095
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002168206.1Primary protein accession used for annex mappings.
UniProt accessionR8N3G0Primary UniProt accession resolved in the annex database.
UniProt IDR8N3G0_BACCXDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagP4U35_RS12130Primary locus identifier stored in the genes table.
Old locus tagP4U35_12095Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JARMBU010000009.1Sequence record reported by the local genomic context database.
Genomic interval263 746-265 122 nt1 377 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span263 106-265 122 ntGCF_036211545::NZ_JARMBU010000009.1::G00041

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_036211545::NZ_JARMBU010000009.1::G00041

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JARMBU010000009.1All displayed genes belong to this local TCS context.
Neighborhood span263 106-265 122 nt2 017 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
263 106 nt265 122 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

P4U35_RS12125GCF_036211545#P4U35_RS12125
RROmpR

263 106-263 753 nt · Forward (+)

Old locus P4U35_12090RefSeq WP_002168205.1
P4U35_RS12130GCF_036211545#P4U35_RS12130
HKClassicCurrent focus

263 746-265 122 nt · Forward (+)

Old locus P4U35_12095RefSeq WP_002168206.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1858247Run 6 · HK · 48 sequences
Representative sequenceGCF_000003925#BMYCO0001_RS12395Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1858247

Simplified PFAM architecture for HKOC_1858247

PFAM domain coverage: 206 / 458 aa (45.0%)

1 aa458 aa
HAMP: 182-232 aaHAMPHisKA: 245-303 aaHisKAHATPase_c: 350-445 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[182-232] | HisKA[245-303] | HATPase_c[350-445]
  • Domain count: 3
  • Matched identifier: HKOC_1858247
  • Positioned domains: HAMP 182-232 ; HisKA 245-303 ; HATPase_c 350-445
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003925#BMYCO0001_RS12395

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 405 · GCF_036211545
AssemblyASM3621154v1 · Scaffoldhaploid
Genome composition5 565 022 bp · 35,0% GCBacillus mycoides
Signal transduction countsGenes 133 · HK 70 · RR 62CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderBacillalesFamilyBacillaceaeGenusBacillus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Bacillales6Bacillaceae7Bacillus

Related genes

Preview from the same derived genome key