1 HisKA#1
29-88 aa · 60 aa · 23.6% of protein
Raw token
HisKA:29:0.00000000627:88:60:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
U0C74_RS10535
Histidine kinase, Classic
Clostridioides difficile · GCF_034318345
ClassHKTypeClassicLength254 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_034318345#U0C74_RS10535Stable P2CS identifier used across views.
GenomeGCF_034318345Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length254 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage166 / 254 aa (65.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa254 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
145-250 aa · 106 aa · 41.7% of protein
Raw token
HATPase_c:145:2.82e-29:250:106:109- Raw architecture: HisKA:29:0.00000000627:88:60:64#HATPase_c:145:2.82e-29:250:106:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_034318345::NZ_JAXKUX010000028.1::G00028
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span28124-29960Genomic interval covered by the local TCS group.
Identifiers
Old locus tagU0C74_10535RefSeq proteinWP_223380601.1
Context group ID
GCF_034318345::NZ_JAXKUX010000028.1::G00028Context members
U0C74_RS10530U0C74_RS10535
Partner locus tags
U0C74_RS10530U0C74_RS10535
Partner old locus tags
U0C74_10530U0C74_10535
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_223380601.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagU0C74_RS10535Primary locus identifier stored in the genes table.
Old locus tagU0C74_10535Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAXKUX010000028.1Sequence record reported by the local genomic context database.
Genomic interval29 196-29 960 nt765 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span28 124-29 960 ntGCF_034318345::NZ_JAXKUX010000028.1::G00028
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_034318345::NZ_JAXKUX010000028.1::G00028Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAXKUX010000028.1All displayed genes belong to this local TCS context.
Neighborhood span28 124-29 960 nt1 837 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
28 124 nt29 960 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
U0C74_RS10530GCF_034318345#U0C74_RS10530
RROmpR
28 124-28 858 nt · Forward (+)
U0C74_RS10535GCF_034318345#U0C74_RS10535
HKClassicCurrent focus
29 196-29 960 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000582865#BN165_RS00200Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2511819
Simplified PFAM architecture for HKOC_2511819
PFAM domain coverage: 167 / 392 aa (42.6%)
1 aa392 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[167-226] | HATPase_c[283-389]
- Domain count: 2
- Matched identifier: HKOC_2511819
- Positioned domains: HisKA 167-226 ; HATPase_c 283-389
Cluster members and taxonomy
Representative gene: GCF_000582865#BN165_RS00200
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_034318345
AssemblyASM3431834v1 · Scaffoldhaploid
Genome composition4 005 747 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 96 · HK 48 · RR 48CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key