Gene detail

U0C50_RS07195

Histidine kinase, Classic

Clostridioides difficile · GCF_034318245

ClassHKTypeClassicLength425 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_034318245#U0C50_RS07195Stable P2CS identifier used across views.
GenomeGCF_034318245Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2082201Run 6 · 595 sequences · id 100% · cov 80%
External referencesWP_322141809.1 · MIST4 U0C50_RS07195RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length425 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage211 / 425 aa (49.6%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa425 aa
HAMP: 144-211 aa (68 aa)1HisKA: 232-296 aa (65 aa)2HATPase_c: 342-419 aa (78 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
144-211 aa · 68 aa · 16.0% of protein
Raw tokenHAMP:144:0.000000219:211:68:69
2 HisKA#2
232-296 aa · 65 aa · 15.3% of protein
Raw tokenHisKA:232:0.00000508:296:65:64
3 HATPase_c#3
342-419 aa · 78 aa · 18.4% of protein
Raw tokenHATPase_c:342:0.00000505:419:90:109
  • Raw architecture: HAMP:144:0.000000219:211:68:69#HisKA:232:0.00000508:296:65:64#HATPase_c:342:0.00000505:419:90:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_034318245::NZ_JAXKVG010000017.1::G00021
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span60394-62319Genomic interval covered by the local TCS group.
Identifiers
Old locus tagU0C50_07195RefSeq proteinWP_322141809.1
Context group IDGCF_034318245::NZ_JAXKVG010000017.1::G00021
Context members
U0C50_RS07190U0C50_RS07195
Partner locus tags
U0C50_RS07190U0C50_RS07195
Partner old locus tags
U0C50_07190U0C50_07195
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_322141809.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagU0C50_RS07195Primary locus identifier stored in the genes table.
Old locus tagU0C50_07195Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAXKVG010000017.1Sequence record reported by the local genomic context database.
Genomic interval61 044-62 319 nt1 276 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span60 394-62 319 ntGCF_034318245::NZ_JAXKVG010000017.1::G00021

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_034318245::NZ_JAXKVG010000017.1::G00021

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAXKVG010000017.1All displayed genes belong to this local TCS context.
Neighborhood span60 394-62 319 nt1 926 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
60 394 nt62 319 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

U0C50_RS07190GCF_034318245#U0C50_RS07190
RROmpR

60 394-61 047 nt · Forward (+)

Old locus U0C50_07190RefSeq WP_002285815.1
U0C50_RS07195GCF_034318245#U0C50_RS07195
HKClassicCurrent focus

61 044-62 319 nt · Forward (+)

Old locus U0C50_07195RefSeq WP_322141809.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2082201Run 6 · HK · 595 sequences
Representative sequenceGCF_000003215#QAC_RS0217010Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2082201

Simplified PFAM architecture for HKOC_2082201

PFAM domain coverage: 143 / 439 aa (32.6%)

1 aa439 aa
HisKA: 233-296 aaHisKAHATPase_c: 342-420 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[233-296] | HATPase_c[342-420]
  • Domain count: 2
  • Matched identifier: HKOC_2082201
  • Positioned domains: HisKA 233-296 ; HATPase_c 342-420
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0217010

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_034318245
AssemblyASM3431824v1 · Scaffoldhaploid
Genome composition4 189 059 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key