1 GAF_3#1
98-221 aa · 124 aa · 26.7% of protein
Raw token
GAF_3:98:0.00000216:221:131:129P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
U0C50_RS06935
Histidine kinase, Classic
Clostridioides difficile · GCF_034318245
ClassHKTypeClassicLength465 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_034318245#U0C50_RS06935Stable P2CS identifier used across views.
GenomeGCF_034318245Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
GAF_3HisKAHATPase_c
Protein length465 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage305 / 465 aa (65.6%)Merged over positioned domains only.
Domain description1 GAF_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa465 aa
Domain-by-domain annotation3 items
2 HisKA#2
241-308 aa · 68 aa · 14.6% of protein
Raw token
HisKA:241:0.00000000000256:308:68:643 HATPase_c#3
352-464 aa · 113 aa · 24.3% of protein
Raw token
HATPase_c:352:8.93e-31:464:113:109- Raw architecture: GAF_3:98:0.00000216:221:131:129#HisKA:241:0.00000000000256:308:68:64#HATPase_c:352:8.93e-31:464:113:109
- Domain description: 1 GAF_3,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_034318245::NZ_JAXKVG010000017.1::G00020
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1-2130Genomic interval covered by the local TCS group.
Identifiers
Old locus tagU0C50_06935RefSeq proteinWP_322141808.1
Context group ID
GCF_034318245::NZ_JAXKVG010000017.1::G00020Context members
U0C50_RS06935U0C50_RS06940
Partner locus tags
U0C50_RS06935U0C50_RS06940
Partner old locus tags
U0C50_06935U0C50_06940
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_322141808.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagU0C50_RS06935Primary locus identifier stored in the genes table.
Old locus tagU0C50_06935Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAXKVG010000017.1Sequence record reported by the local genomic context database.
Genomic interval1-1 398 nt1 398 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1-2 130 ntGCF_034318245::NZ_JAXKVG010000017.1::G00020
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_034318245::NZ_JAXKVG010000017.1::G00020Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAXKVG010000017.1All displayed genes belong to this local TCS context.
Neighborhood span1-2 130 nt2 130 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt2 130 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
U0C50_RS06935GCF_034318245#U0C50_RS06935
HKClassicCurrent focus
1-1 398 nt · Forward (+)
U0C50_RS06940GCF_034318245#U0C50_RS06940
RROmpR
1 432-2 130 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000009205#CD630_RS09955Use this link to inspect the representative gene detail.
PFAM architectureKdpD + DUF4118 + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0405628
Simplified PFAM architecture for HKOC_0405628
PFAM domain coverage: 494 / 900 aa (54.9%)
1 aa900 aa
KdpDDUF4118HisKAHATPase_c
- Simplified architecture: KdpD + DUF4118 + HisKA + HATPase_c
- Raw architecture: KdpD[22-230] | DUF4118[409-514] | HisKA[676-743] | HATPase_c[788-898]
- Domain count: 4
- Matched identifier: HKOC_0405628
- Positioned domains: KdpD 22-230 ; DUF4118 409-514 ; HisKA 676-743 ; HATPase_c 788-898
Cluster members and taxonomy
Representative gene: GCF_000009205#CD630_RS09955
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_034318245
AssemblyASM3431824v1 · Scaffoldhaploid
Genome composition4 189 059 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key