1 HisKA#1
245-309 aa · 65 aa · 14.5% of protein
Raw token
HisKA:245:0.00000000000142:309:65:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
CDIFB12_RS03660
Histidine kinase, Classic
Clostridioides difficile · GCF_034272075
ClassHKTypeClassicLength447 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_034272075#CDIFB12_RS03660Stable P2CS identifier used across views.
GenomeGCF_034272075Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length447 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage153 / 447 aa (34.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa447 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
357-444 aa · 88 aa · 19.7% of protein
Raw token
HATPase_c:357:0.00000000000167:444:89:109- Raw architecture: HisKA:245:0.00000000000142:309:65:64#HATPase_c:357:0.00000000000167:444:89:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_034272075::NZ_CP132141.1::G00013
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span756546-758641Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDIFB12_07300RefSeq proteinWP_236872490.1
Context group ID
GCF_034272075::NZ_CP132141.1::G00013Context members
CDIFB12_RS03655CDIFB12_RS03660
Partner locus tags
CDIFB12_RS03655CDIFB12_RS03660
Partner old locus tags
CDIFB12_07290CDIFB12_07300
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_236872490.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagCDIFB12_RS03660Primary locus identifier stored in the genes table.
Old locus tagCDIFB12_07300Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP132141.1Sequence record reported by the local genomic context database.
Genomic interval757 298-758 641 nt1 344 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span756 546-758 641 ntGCF_034272075::NZ_CP132141.1::G00013
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_034272075::NZ_CP132141.1::G00013Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP132141.1All displayed genes belong to this local TCS context.
Neighborhood span756 546-758 641 nt2 096 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
756 546 nt758 641 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
CDIFB12_RS03655GCF_034272075#CDIFB12_RS03655
RROmpR
756 546-757 253 nt · Forward (+)
CDIFB12_RS03660GCF_034272075#CDIFB12_RS03660
HKClassicCurrent focus
757 298-758 641 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_017310685#JQS07_RS04170Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2004207
Simplified PFAM architecture for HKOC_2004207
PFAM domain coverage: 153 / 447 aa (34.2%)
1 aa447 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[245-310] | HATPase_c[358-444]
- Domain count: 2
- Matched identifier: HKOC_2004207
- Positioned domains: HisKA 245-310 ; HATPase_c 358-444
Cluster members and taxonomy
Representative gene: GCF_017310685#JQS07_RS04170
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_034272075
AssemblyASM3427207v1 · Complete Genomehaploid
Genome composition4 244 212 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 46 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key