Gene detail

SRA80_RS14650

Histidine kinase, Classic

Clostridioides difficile · GCF_034188625

ClassHKTypeClassicLength474 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_034188625#SRA80_RS14650Stable P2CS identifier used across views.
GenomeGCF_034188625Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1678889Run 6 · 7 sequences · id 100% · cov 80%
External referencesWP_133145791.1 · MIST4 SRA80_RS14650RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length474 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 474 aa (53.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa474 aa
HAMP: 161-238 aa (78 aa)1HisKA: 250-315 aa (66 aa)2HATPase_c: 365-471 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
161-238 aa · 78 aa · 16.5% of protein
Raw tokenHAMP:161:0.0000000138:238:78:69
2 HisKA#2
250-315 aa · 66 aa · 13.9% of protein
Raw tokenHisKA:250:0.00000000206:315:66:64
3 HATPase_c#3
365-471 aa · 107 aa · 22.6% of protein
Raw tokenHATPase_c:365:5.48e-26:471:107:109
  • Raw architecture: HAMP:161:0.0000000138:238:78:69#HisKA:250:0.00000000206:315:66:64#HATPase_c:365:5.48e-26:471:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_034188625::NZ_JAXHQO010000017.1::G00044
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span123966-126101Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSRA80_14670RefSeq proteinWP_133145791.1
Context group IDGCF_034188625::NZ_JAXHQO010000017.1::G00044
Context members
SRA80_RS14645SRA80_RS14650
Partner locus tags
SRA80_RS14645SRA80_RS14650
Partner old locus tags
SRA80_14665SRA80_14670
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_133145791.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagSRA80_RS14650Primary locus identifier stored in the genes table.
Old locus tagSRA80_14670Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAXHQO010000017.1Sequence record reported by the local genomic context database.
Genomic interval124 677-126 101 nt1 425 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span123 966-126 101 ntGCF_034188625::NZ_JAXHQO010000017.1::G00044

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_034188625::NZ_JAXHQO010000017.1::G00044

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAXHQO010000017.1All displayed genes belong to this local TCS context.
Neighborhood span123 966-126 101 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
123 966 nt126 101 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

SRA80_RS14645GCF_034188625#SRA80_RS14645
RROmpR

123 966-124 658 nt · Forward (+)

Old locus SRA80_14665RefSeq WP_003434748.1
SRA80_RS14650GCF_034188625#SRA80_RS14650
HKClassicCurrent focus

124 677-126 101 nt · Forward (+)

Old locus SRA80_14670RefSeq WP_133145791.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1678889Run 6 · HK · 7 sequences
Representative sequenceGCF_011882285#GSQ25_RS04195Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1678889

Simplified PFAM architecture for HKOC_1678889

PFAM domain coverage: 223 / 474 aa (47.0%)

1 aa474 aa
HAMP: 188-238 aaHAMPHisKA: 251-315 aaHisKAHATPase_c: 365-471 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[188-238] | HisKA[251-315] | HATPase_c[365-471]
  • Domain count: 3
  • Matched identifier: HKOC_1678889
  • Positioned domains: HAMP 188-238 ; HisKA 251-315 ; HATPase_c 365-471
Cluster members and taxonomy
Visualization

Representative gene: GCF_011882285#GSQ25_RS04195

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_034188625
AssemblyASM3418862v1 · Contighaploid
Genome composition4 225 642 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 48 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key