Gene detail

SRH14_RS00250

Histidine kinase, Classic

Clostridioides difficile · GCF_034188565

ClassHKTypeClassicLength300 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_034188565#SRH14_RS00250Stable P2CS identifier used across views.
GenomeGCF_034188565Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2887336Run 6 · 3 sequences · id 100% · cov 80%
External referencesWP_321119221.1 · MIST4 SRH14_RS00250RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length300 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage160 / 300 aa (53.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa300 aa
HisKA: 90-150 aa (61 aa)1HATPase_c: 197-295 aa (99 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
90-150 aa · 61 aa · 20.3% of protein
Raw tokenHisKA:90:0.0000000000133:150:61:64
2 HATPase_c#2
197-295 aa · 99 aa · 33.0% of protein
Raw tokenHATPase_c:197:2.39e-17:295:105:109
  • Raw architecture: HisKA:90:0.0000000000133:150:61:64#HATPase_c:197:2.39e-17:295:105:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_034188565::NZ_JAXHSA010000001.1::G00002
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span56289-57191Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSRH14_00250RefSeq proteinWP_321119221.1
Context group IDGCF_034188565::NZ_JAXHSA010000001.1::G00002
Context members
SRH14_RS00250
Partner locus tags
SRH14_RS00250
Partner old locus tags
SRH14_00250
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_321119221.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagSRH14_RS00250Primary locus identifier stored in the genes table.
Old locus tagSRH14_00250Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAXHSA010000001.1Sequence record reported by the local genomic context database.
Genomic interval56 289-57 191 nt903 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span56 289-57 191 ntGCF_034188565::NZ_JAXHSA010000001.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_034188565::NZ_JAXHSA010000001.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAXHSA010000001.1All displayed genes belong to this local TCS context.
Neighborhood span56 289-57 191 nt903 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
56 289 nt57 191 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

SRH14_RS00250GCF_034188565#SRH14_RS00250
HKClassicCurrent focus

56 289-57 191 nt · Forward (+)

Old locus SRH14_00250RefSeq WP_321119221.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2887336Run 6 · HK · 3 sequences
Representative sequenceGCF_034188375#SRP14_RS06525Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2887336

Simplified PFAM architecture for HKOC_2887336

PFAM domain coverage: 157 / 300 aa (52.3%)

1 aa300 aa
HisKA: 89-148 aaHisKAHATPase_c: 199-295 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[89-148] | HATPase_c[199-295]
  • Domain count: 2
  • Matched identifier: HKOC_2887336
  • Positioned domains: HisKA 89-148 ; HATPase_c 199-295
Cluster members and taxonomy
Visualization

Representative gene: GCF_034188375#SRP14_RS06525

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_034188565
AssemblyASM3418856v1 · Contighaploid
Genome composition4 082 617 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 51 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key