Gene detail

SRJ00_RS00640

Histidine kinase, Classic

Clostridioides difficile · GCF_034188355

ClassHKTypeClassicLength778 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_034188355#SRJ00_RS00640Stable P2CS identifier used across views.
GenomeGCF_034188355Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0599081Run 6 · 50 sequences · id 100% · cov 80%
External referencesWP_231301863.1 · MIST4 SRJ00_RS00640RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length778 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage172 / 778 aa (22.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for SRJ00_RS00640
Domain-by-domain annotation2 items
1 HisKA#1
558-624 aa · 67 aa · 8.6% of protein
Raw tokenHisKA:558:1.37e-18:624:67:64
2 HATPase_c#2
671-775 aa · 105 aa · 13.5% of protein
Raw tokenHATPase_c:671:0.000000000406:775:110:109
  • Raw architecture: HisKA:558:1.37e-18:624:67:64#HATPase_c:671:0.000000000406:775:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_034188355::NZ_JAXHRU010000001.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span138953-141977Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSRJ00_00640RefSeq proteinWP_231301863.1
Context group IDGCF_034188355::NZ_JAXHRU010000001.1::G00003
Context members
SRJ00_RS00635SRJ00_RS00640
Partner locus tags
SRJ00_RS00635SRJ00_RS00640
Partner old locus tags
SRJ00_00635SRJ00_00640
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_231301863.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagSRJ00_RS00640Primary locus identifier stored in the genes table.
Old locus tagSRJ00_00640Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAXHRU010000001.1Sequence record reported by the local genomic context database.
Genomic interval139 641-141 977 nt2 337 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span138 953-141 977 ntGCF_034188355::NZ_JAXHRU010000001.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_034188355::NZ_JAXHRU010000001.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAXHRU010000001.1All displayed genes belong to this local TCS context.
Neighborhood span138 953-141 977 nt3 025 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
138 953 nt141 977 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

SRJ00_RS00635GCF_034188355#SRJ00_RS00635
RROmpR

138 953-139 669 nt · Forward (+)

Old locus SRJ00_00635RefSeq WP_003431132.1
SRJ00_RS00640GCF_034188355#SRJ00_RS00640
HKClassicCurrent focus

139 641-141 977 nt · Forward (+)

Old locus SRJ00_00640RefSeq WP_231301863.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0599081Run 6 · HK · 50 sequences
Representative sequenceGCF_000451745#QSK_RS12970Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0599081

Simplified PFAM architecture for HKOC_0599081

PFAM domain coverage: 172 / 778 aa (22.1%)

1 aa778 aa
HisKA: 558-624 aaHisKAHATPase_c: 671-775 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[558-624] | HATPase_c[671-775]
  • Domain count: 2
  • Matched identifier: HKOC_0599081
  • Positioned domains: HisKA 558-624 ; HATPase_c 671-775
Cluster members and taxonomy
Visualization

Representative gene: GCF_000451745#QSK_RS12970

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_034188355
AssemblyASM3418835v1 · Contighaploid
Genome composition4 320 668 bp · 29,5% GCClostridioides difficile
Signal transduction countsGenes 104 · HK 49 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key