1 PAS_8#1
423-460 aa · 38 aa · 4.7% of protein
Raw token
PAS_8:423:0.0000631:460:38:65P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
SIK60_RS15180
Histidine kinase, Classic
Clostridioides difficile · GCF_033841335
ClassHKTypeClassicLength803 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_033841335#SIK60_RS15180Stable P2CS identifier used across views.
GenomeGCF_033841335Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
PAS_8HisKAHATPase_c
Protein length803 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage222 / 803 aa (27.6%)Merged over positioned domains only.
Domain description1 PAS_8,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa803 aa
Domain-by-domain annotation3 items
2 HisKA#2
546-617 aa · 72 aa · 9.0% of protein
Raw token
HisKA:546:0.0000000017:617:72:643 HATPase_c#3
665-776 aa · 112 aa · 13.9% of protein
Raw token
HATPase_c:665:7.79e-26:776:112:109- Raw architecture: PAS_8:423:0.0000631:460:38:65#HisKA:546:0.0000000017:617:72:64#HATPase_c:665:7.79e-26:776:112:109
- Domain description: 1 PAS_8,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_033841335::NZ_JAWXSG010000127.1::G00005
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span7424-9836Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSIK60_15165RefSeq proteinWP_320073401.1
Context group ID
GCF_033841335::NZ_JAWXSG010000127.1::G00005Context members
SIK60_RS15180
Partner locus tags
SIK60_RS15180
Partner old locus tags
SIK60_15165
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_320073401.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagSIK60_RS15180Primary locus identifier stored in the genes table.
Old locus tagSIK60_15165Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAWXSG010000127.1Sequence record reported by the local genomic context database.
Genomic interval7 424-9 836 nt2 413 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span7 424-9 836 ntGCF_033841335::NZ_JAWXSG010000127.1::G00005
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_033841335::NZ_JAWXSG010000127.1::G00005Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAWXSG010000127.1All displayed genes belong to this local TCS context.
Neighborhood span7 424-9 836 nt2 413 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
7 424 nt9 836 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
SIK60_RS15180GCF_033841335#SIK60_RS15180
HKClassicCurrent focus
7 424-9 836 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000235905#HMPREF9945_RS16670Use this link to inspect the representative gene detail.
PFAM architecturePAS_8 + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0387840
Simplified PFAM architecture for HKOC_0387840
PFAM domain coverage: 221 / 912 aa (24.2%)
1 aa912 aa
PAS_8HisKAHATPase_c
- Simplified architecture: PAS_8 + HisKA + HATPase_c
- Raw architecture: PAS_8[532-572] | HisKA[656-724] | HATPase_c[774-884]
- Domain count: 3
- Matched identifier: HKOC_0387840
- Positioned domains: PAS_8 532-572 ; HisKA 656-724 ; HATPase_c 774-884
Cluster members and taxonomy
Representative gene: GCF_000235905#HMPREF9945_RS16670
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_033841335
AssemblyASM3384133v1 · Contighaploid
Genome composition4 087 268 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 47 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key