1 HAMP#1
180-247 aa · 68 aa · 14.7% of protein
Raw token
HAMP:180:0.00000723:247:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
SIK60_RS12080
Histidine kinase, Classic
Clostridioides difficile · GCF_033841335
ClassHKTypeClassicLength463 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_033841335#SIK60_RS12080Stable P2CS identifier used across views.
GenomeGCF_033841335Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length463 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 463 aa (49.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa463 aa
Domain-by-domain annotation3 items
2 HisKA#2
257-315 aa · 59 aa · 12.7% of protein
Raw token
HisKA:257:4.74e-17:315:59:643 HATPase_c#3
363-463 aa · 101 aa · 21.8% of protein
Raw token
HATPase_c:363:2.34e-27:463:106:109- Raw architecture: HAMP:180:0.00000723:247:68:69#HisKA:257:4.74e-17:315:59:64#HATPase_c:363:2.34e-27:463:106:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_033841335::NZ_JAWXSG010000075.1::G00051
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span16743-18134Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSIK60_12070RefSeq proteinWP_320073360.1
Context group ID
GCF_033841335::NZ_JAWXSG010000075.1::G00051Context members
SIK60_RS12080
Partner locus tags
SIK60_RS12080
Partner old locus tags
SIK60_12070
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_320073360.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagSIK60_RS12080Primary locus identifier stored in the genes table.
Old locus tagSIK60_12070Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAWXSG010000075.1Sequence record reported by the local genomic context database.
Genomic interval16 743-18 134 nt1 392 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span16 743-18 134 ntGCF_033841335::NZ_JAWXSG010000075.1::G00051
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_033841335::NZ_JAWXSG010000075.1::G00051Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAWXSG010000075.1All displayed genes belong to this local TCS context.
Neighborhood span16 743-18 134 nt1 392 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
16 743 nt18 134 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
SIK60_RS12080GCF_033841335#SIK60_RS12080
HKClassicCurrent focus
16 743-18 134 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000155025#UAB_RS0205810Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1504291
Simplified PFAM architecture for HKOC_1504291
PFAM domain coverage: 161 / 495 aa (32.5%)
1 aa495 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[287-347] | HATPase_c[395-494]
- Domain count: 2
- Matched identifier: HKOC_1504291
- Positioned domains: HisKA 287-347 ; HATPase_c 395-494
Cluster members and taxonomy
Representative gene: GCF_000155025#UAB_RS0205810
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_033841335
AssemblyASM3384133v1 · Contighaploid
Genome composition4 087 268 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 47 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key