1 PAS_4#1
247-355 aa · 109 aa · 17.6% of protein
Raw token
PAS_4:247:0.000000000203:355:115:110P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
SIK60_RS06780
Histidine kinase, Classic
Clostridioides difficile · GCF_033841335
ClassHKTypeClassicLength619 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_033841335#SIK60_RS06780Stable P2CS identifier used across views.
GenomeGCF_033841335Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
PAS_4HisKAHATPase_c
Protein length619 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage290 / 619 aa (46.8%)Merged over positioned domains only.
Domain description1 PAS_4,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa619 aa
Domain-by-domain annotation3 items
2 HisKA#2
364-433 aa · 70 aa · 11.3% of protein
Raw token
HisKA:364:0.00000000000000112:433:70:643 HATPase_c#3
480-590 aa · 111 aa · 17.9% of protein
Raw token
HATPase_c:480:8.17e-28:590:111:109- Raw architecture: PAS_4:247:0.000000000203:355:115:110#HisKA:364:0.00000000000000112:433:70:64#HATPase_c:480:8.17e-28:590:111:109
- Domain description: 1 PAS_4,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_033841335::NZ_JAWXSG010000029.1::G00032
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span30396-32256Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSIK60_06775RefSeq proteinWP_320073317.1
Context group ID
GCF_033841335::NZ_JAWXSG010000029.1::G00032Context members
SIK60_RS06780
Partner locus tags
SIK60_RS06780
Partner old locus tags
SIK60_06775
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_320073317.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagSIK60_RS06780Primary locus identifier stored in the genes table.
Old locus tagSIK60_06775Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAWXSG010000029.1Sequence record reported by the local genomic context database.
Genomic interval30 396-32 256 nt1 861 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span30 396-32 256 ntGCF_033841335::NZ_JAWXSG010000029.1::G00032
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_033841335::NZ_JAWXSG010000029.1::G00032Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAWXSG010000029.1All displayed genes belong to this local TCS context.
Neighborhood span30 396-32 256 nt1 861 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
30 396 nt32 256 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
SIK60_RS06780GCF_033841335#SIK60_RS06780
HKClassicCurrent focus
30 396-32 256 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_033841335#SIK60_RS06780The current gene is the representative for this cluster.
PFAM architecturePAS_4 + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0976756
Simplified PFAM architecture for HKOC_0976756
PFAM domain coverage: 290 / 619 aa (46.8%)
1 aa619 aa
PAS_4HisKAHATPase_c
- Simplified architecture: PAS_4 + HisKA + HATPase_c
- Raw architecture: PAS_4[247-355] | HisKA[364-433] | HATPase_c[480-590]
- Domain count: 3
- Matched identifier: HKOC_0976756
- Positioned domains: PAS_4 247-355 ; HisKA 364-433 ; HATPase_c 480-590
Cluster members and taxonomy
Representative gene: GCF_033841335#SIK60_RS06780
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_033841335
AssemblyASM3384133v1 · Contighaploid
Genome composition4 087 268 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 47 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key