Gene detail

SIK40_RS02695

Histidine kinase, Classic

Clostridioides difficile · GCF_033840485

ClassHKTypeClassicLength399 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_033840485#SIK40_RS02695Stable P2CS identifier used across views.
GenomeGCF_033840485Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2456075Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_320070286.1 · MIST4 SIK40_RS02695RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length399 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage153 / 399 aa (38.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa399 aa
HisKA: 178-244 aa (67 aa)1HATPase_c: 297-382 aa (86 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
178-244 aa · 67 aa · 16.8% of protein
Raw tokenHisKA:178:0.0000000000000159:244:67:64
2 HATPase_c#2
297-382 aa · 86 aa · 21.6% of protein
Raw tokenHATPase_c:297:0.0000000489:382:90:109
  • Raw architecture: HisKA:178:0.0000000000000159:244:67:64#HATPase_c:297:0.0000000489:382:90:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_033840485::NZ_JAWXRN010000025.1::G00014
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1-1200Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSIK40_02695RefSeq proteinWP_320070286.1
Context group IDGCF_033840485::NZ_JAWXRN010000025.1::G00014
Context members
SIK40_RS02695
Partner locus tags
SIK40_RS02695
Partner old locus tags
SIK40_02695
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_320070286.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagSIK40_RS02695Primary locus identifier stored in the genes table.
Old locus tagSIK40_02695Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAWXRN010000025.1Sequence record reported by the local genomic context database.
Genomic interval1-1 200 nt1 200 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1-1 200 ntGCF_033840485::NZ_JAWXRN010000025.1::G00014

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_033840485::NZ_JAWXRN010000025.1::G00014

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAWXRN010000025.1All displayed genes belong to this local TCS context.
Neighborhood span1-1 200 nt1 200 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt1 200 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2456075Run 6 · HK · 1 sequences
Representative sequenceGCF_033840485#SIK40_RS02695The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2456075

Simplified PFAM architecture for HKOC_2456075

PFAM domain coverage: 192 / 399 aa (48.1%)

1 aa399 aa
HAMP: 124-165 aaHAMPHisKA: 179-244 aaHisKAHATPase_c: 296-379 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[124-165] | HisKA[179-244] | HATPase_c[296-379]
  • Domain count: 3
  • Matched identifier: HKOC_2456075
  • Positioned domains: HAMP 124-165 ; HisKA 179-244 ; HATPase_c 296-379
Cluster members and taxonomy
Visualization

Representative gene: GCF_033840485#SIK40_RS02695

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_033840485
AssemblyASM3384048v1 · Contighaploid
Genome composition3 931 618 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 91 · HK 39 · RR 49CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key