1 HisKA#1
449-514 aa · 66 aa · 9.8% of protein
Raw token
HisKA:449:0.00000000477:514:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
SIK48_RS18045
Histidine kinase, Classic
Clostridioides difficile · GCF_033840445
ClassHKTypeClassicLength671 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_033840445#SIK48_RS18045Stable P2CS identifier used across views.
GenomeGCF_033840445Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length671 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage168 / 671 aa (25.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa671 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
567-668 aa · 102 aa · 15.2% of protein
Raw token
HATPase_c:567:1.43e-29:668:102:109- Raw architecture: HisKA:449:0.00000000477:514:66:64#HATPase_c:567:1.43e-29:668:102:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_033840445::NZ_JAWXRM010000234.1::G00020
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span422-3186Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSIK48_18110RefSeq proteinWP_045146397.1
Context group ID
GCF_033840445::NZ_JAWXRM010000234.1::G00020Context members
SIK48_RS18040SIK48_RS18045
Partner locus tags
SIK48_RS18040SIK48_RS18045
Partner old locus tags
SIK48_18105SIK48_18110
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_045146397.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagSIK48_RS18045Primary locus identifier stored in the genes table.
Old locus tagSIK48_18110Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAWXRM010000234.1Sequence record reported by the local genomic context database.
Genomic interval1 171-3 186 nt2 016 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span422-3 186 ntGCF_033840445::NZ_JAWXRM010000234.1::G00020
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_033840445::NZ_JAWXRM010000234.1::G00020Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAWXRM010000234.1All displayed genes belong to this local TCS context.
Neighborhood span422-3 186 nt2 765 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
422 nt3 186 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
SIK48_RS18040GCF_033840445#SIK48_RS18040
RROmpR
422-1 099 nt · Forward (+)
SIK48_RS18045GCF_033840445#SIK48_RS18045
HKClassicCurrent focus
1 171-3 186 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_001704795#DCQ01_RS09510Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0842874
Simplified PFAM architecture for HKOC_0842874
PFAM domain coverage: 168 / 671 aa (25.0%)
1 aa671 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[450-514] | HATPase_c[565-667]
- Domain count: 2
- Matched identifier: HKOC_0842874
- Positioned domains: HisKA 450-514 ; HATPase_c 565-667
Cluster members and taxonomy
Representative gene: GCF_001704795#DCQ01_RS09510
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_033840445
AssemblyASM3384044v1 · Contighaploid
Genome composition3 979 416 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 90 · HK 42 · RR 47CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key