1 H_kinase_N#1
12-142 aa · 131 aa · 27.9% of protein
Raw token
H_kinase_N:12:4.4e-37:142:132:139P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
SIK43_RS06165
Histidine kinase, Classic
Clostridioides difficile · GCF_033840405
ClassHKTypeClassicLength469 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_033840405#SIK43_RS06165Stable P2CS identifier used across views.
GenomeGCF_033840405Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
H_kinase_NHisKA_2HATPase_c
Protein length469 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage304 / 469 aa (64.8%)Merged over positioned domains only.
Domain description1 H_kinase_N,1 HisKA_2,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa469 aa
Domain-by-domain annotation3 items
2 HisKA_2#2
276-350 aa · 75 aa · 16.0% of protein
Raw token
HisKA_2:276:2.55e-16:350:76:763 HATPase_c#3
370-467 aa · 98 aa · 20.9% of protein
Raw token
HATPase_c:370:0.000000206:467:114:109- Raw architecture: H_kinase_N:12:4.4e-37:142:132:139#HisKA_2:276:2.55e-16:350:76:76#HATPase_c:370:0.000000206:467:114:109
- Domain description: 1 H_kinase_N,1 HisKA_2,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_033840405::NZ_JAWXRL010000032.1::G00033
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2425-4402Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSIK43_06155RefSeq proteinWP_003428684.1
Context group ID
GCF_033840405::NZ_JAWXRL010000032.1::G00033Context members
SIK43_RS06160SIK43_RS06165
Partner locus tags
SIK43_RS06160SIK43_RS06165
Partner old locus tags
SIK43_06150SIK43_06155
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003428684.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P3YKS6Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P3YKS6_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagSIK43_RS06165Primary locus identifier stored in the genes table.
Old locus tagSIK43_06155Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAWXRL010000032.1Sequence record reported by the local genomic context database.
Genomic interval2 993-4 402 nt1 410 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 425-4 402 ntGCF_033840405::NZ_JAWXRL010000032.1::G00033
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_033840405::NZ_JAWXRL010000032.1::G00033Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAWXRL010000032.1All displayed genes belong to this local TCS context.
Neighborhood span2 425-4 402 nt1 978 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 425 nt4 402 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
SIK43_RS06160GCF_033840405#SIK43_RS06160
RRAmiR_NasR
2 425-3 000 nt · Forward (+)
SIK43_RS06165GCF_033840405#SIK43_RS06165
HKClassicCurrent focus
2 993-4 402 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000210395#CDM68_RS09835Use this link to inspect the representative gene detail.
PFAM architectureGAF_PdtaS + HisKA_2 + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1727043
Simplified PFAM architecture for HKOC_1727043
PFAM domain coverage: 302 / 469 aa (64.4%)
1 aa469 aa
GAF_PdtaSHisKA_2HATPase_c
- Simplified architecture: GAF_PdtaS + HisKA_2 + HATPase_c
- Raw architecture: GAF_PdtaS[6-141] | HisKA_2[276-347] | HATPase_c[373-466]
- Domain count: 3
- Matched identifier: HKOC_1727043
- Positioned domains: GAF_PdtaS 6-141 ; HisKA_2 276-347 ; HATPase_c 373-466
Cluster members and taxonomy
Representative gene: GCF_000210395#CDM68_RS09835
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_033840405
AssemblyASM3384040v1 · Contighaploid
Genome composition4 119 885 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 43 · RR 52CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key