Gene detail

SIK43_RS03545

Histidine kinase, Classic

Clostridioides difficile · GCF_033840405

ClassHKTypeClassicLength270 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_033840405#SIK43_RS03545Stable P2CS identifier used across views.
GenomeGCF_033840405Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2503353Run 6 · 406 sequences · id 100% · cov 80%
External referencesWP_320061397.1 · MIST4 SIK43_RS03545RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length270 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage176 / 270 aa (65.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa270 aa
HisKA: 45-111 aa (67 aa)1HATPase_c: 157-265 aa (109 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
45-111 aa · 67 aa · 24.8% of protein
Raw tokenHisKA:45:0.0000000000000991:111:67:64
2 HATPase_c#2
157-265 aa · 109 aa · 40.4% of protein
Raw tokenHATPase_c:157:2.22e-27:265:110:109
  • Raw architecture: HisKA:45:0.0000000000000991:111:67:64#HATPase_c:157:2.22e-27:265:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_033840405::NZ_JAWXRL010000014.1::G00009
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1-813Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSIK43_03545RefSeq proteinWP_320061397.1
Context group IDGCF_033840405::NZ_JAWXRL010000014.1::G00009
Context members
SIK43_RS03545
Partner locus tags
SIK43_RS03545
Partner old locus tags
SIK43_03545
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_320061397.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagSIK43_RS03545Primary locus identifier stored in the genes table.
Old locus tagSIK43_03545Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAWXRL010000014.1Sequence record reported by the local genomic context database.
Genomic interval1-813 nt813 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1-813 ntGCF_033840405::NZ_JAWXRL010000014.1::G00009

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_033840405::NZ_JAWXRL010000014.1::G00009

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAWXRL010000014.1All displayed genes belong to this local TCS context.
Neighborhood span1-813 nt813 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt813 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2503353Run 6 · HK · 406 sequences
Representative sequenceGCF_000210395#CDM68_RS18640Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2503353

Simplified PFAM architecture for HKOC_2503353

PFAM domain coverage: 175 / 393 aa (44.5%)

1 aa393 aa
HisKA: 168-233 aaHisKAHATPase_c: 281-389 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[168-233] | HATPase_c[281-389]
  • Domain count: 2
  • Matched identifier: HKOC_2503353
  • Positioned domains: HisKA 168-233 ; HATPase_c 281-389
Cluster members and taxonomy
Visualization

Representative gene: GCF_000210395#CDM68_RS18640

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_033840405
AssemblyASM3384040v1 · Contighaploid
Genome composition4 119 885 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 43 · RR 52CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key