1 HAMP#1
161-238 aa · 78 aa · 16.5% of protein
Raw token
HAMP:161:0.0000000158:238:78:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
SIK43_RS01345
Histidine kinase, Classic
Clostridioides difficile · GCF_033840405
ClassHKTypeClassicLength474 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_033840405#SIK43_RS01345Stable P2CS identifier used across views.
GenomeGCF_033840405Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length474 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 474 aa (53.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa474 aa
Domain-by-domain annotation3 items
2 HisKA#2
250-315 aa · 66 aa · 13.9% of protein
Raw token
HisKA:250:0.00000000176:315:66:643 HATPase_c#3
365-471 aa · 107 aa · 22.6% of protein
Raw token
HATPase_c:365:3.28e-26:471:107:109- Raw architecture: HAMP:161:0.0000000158:238:78:69#HisKA:250:0.00000000176:315:66:64#HATPase_c:365:3.28e-26:471:107:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_033840405::NZ_JAWXRL010000004.1::G00047
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span49774-51909Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSIK43_01345RefSeq proteinWP_003426340.1
Context group ID
GCF_033840405::NZ_JAWXRL010000004.1::G00047Context members
SIK43_RS01340SIK43_RS01345
Partner locus tags
SIK43_RS01340SIK43_RS01345
Partner old locus tags
SIK43_01340SIK43_01345
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003426340.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P3TX80Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P3TX80_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagSIK43_RS01345Primary locus identifier stored in the genes table.
Old locus tagSIK43_01345Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAWXRL010000004.1Sequence record reported by the local genomic context database.
Genomic interval50 485-51 909 nt1 425 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span49 774-51 909 ntGCF_033840405::NZ_JAWXRL010000004.1::G00047
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_033840405::NZ_JAWXRL010000004.1::G00047Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAWXRL010000004.1All displayed genes belong to this local TCS context.
Neighborhood span49 774-51 909 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
49 774 nt51 909 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
SIK43_RS01340GCF_033840405#SIK43_RS01340
RROmpR
49 774-50 466 nt · Forward (+)
SIK43_RS01345GCF_033840405#SIK43_RS01345
HKClassicCurrent focus
50 485-51 909 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000210395#CDM68_RS02680Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1674287
Simplified PFAM architecture for HKOC_1674287
PFAM domain coverage: 223 / 474 aa (47.0%)
1 aa474 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[188-238] | HisKA[251-315] | HATPase_c[365-471]
- Domain count: 3
- Matched identifier: HKOC_1674287
- Positioned domains: HAMP 188-238 ; HisKA 251-315 ; HATPase_c 365-471
Cluster members and taxonomy
Representative gene: GCF_000210395#CDM68_RS02680
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_033840405
AssemblyASM3384040v1 · Contighaploid
Genome composition4 119 885 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 43 · RR 52CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key