1 HAMP#1
62-131 aa · 70 aa · 18.6% of protein
Raw token
HAMP:62:0.0000000000133:131:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
SIK43_RS00615
Histidine kinase, Classic
Clostridioides difficile · GCF_033840405
ClassHKTypeClassicLength376 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_033840405#SIK43_RS00615Stable P2CS identifier used across views.
GenomeGCF_033840405Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length376 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage246 / 376 aa (65.4%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa376 aa
Domain-by-domain annotation3 items
2 HisKA#2
156-221 aa · 66 aa · 17.6% of protein
Raw token
HisKA:156:0.00000000000000434:221:66:643 HATPase_c#3
267-376 aa · 110 aa · 29.3% of protein
Raw token
HATPase_c:267:3.22e-17:376:111:109- Raw architecture: HAMP:62:0.0000000000133:131:70:69#HisKA:156:0.00000000000000434:221:66:64#HATPase_c:267:3.22e-17:376:111:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_033840405::NZ_JAWXRL010000002.1::G00029
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span36902-38700Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSIK43_00615RefSeq proteinWP_003428022.1
Context group ID
GCF_033840405::NZ_JAWXRL010000002.1::G00029Context members
SIK43_RS00610SIK43_RS00615
Partner locus tags
SIK43_RS00610SIK43_RS00615
Partner old locus tags
SIK43_00610SIK43_00615
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003428022.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P3YQ06Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P3YQ06_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagSIK43_RS00615Primary locus identifier stored in the genes table.
Old locus tagSIK43_00615Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAWXRL010000002.1Sequence record reported by the local genomic context database.
Genomic interval37 570-38 700 nt1 131 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span36 902-38 700 ntGCF_033840405::NZ_JAWXRL010000002.1::G00029
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_033840405::NZ_JAWXRL010000002.1::G00029Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAWXRL010000002.1All displayed genes belong to this local TCS context.
Neighborhood span36 902-38 700 nt1 799 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
36 902 nt38 700 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
SIK43_RS00610GCF_033840405#SIK43_RS00610
RROmpR
36 902-37 573 nt · Forward (+)
SIK43_RS00615GCF_033840405#SIK43_RS00615
HKClassicCurrent focus
37 570-38 700 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000210395#CDM68_RS16570Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2641532
Simplified PFAM architecture for HKOC_2641532
PFAM domain coverage: 225 / 376 aa (59.8%)
1 aa376 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[79-130] | HisKA[156-221] | HATPase_c[268-374]
- Domain count: 3
- Matched identifier: HKOC_2641532
- Positioned domains: HAMP 79-130 ; HisKA 156-221 ; HATPase_c 268-374
Cluster members and taxonomy
Representative gene: GCF_000210395#CDM68_RS16570
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_033840405
AssemblyASM3384040v1 · Contighaploid
Genome composition4 119 885 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 43 · RR 52CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key