Gene detail

SBI57_RS11285

Histidine kinase, Classic

Clostridioides difficile · GCF_033239845

ClassHKTypeClassicLength395 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_033239845#SBI57_RS11285Stable P2CS identifier used across views.
GenomeGCF_033239845Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0977609Run 6 · 24 sequences · id 100% · cov 80%
External referencesWP_317911267.1 · MIST4 SBI57_RS11285RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_4HisKAHATPase_c
Protein length395 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage290 / 395 aa (73.4%)Merged over positioned domains only.
Domain description1 PAS_4,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa395 aa
PAS_4: 23-131 aa (109 aa)1HisKA: 140-209 aa (70 aa)2HATPase_c: 256-366 aa (111 aa)3
Domain-by-domain annotation3 items
1 PAS_4#1
23-131 aa · 109 aa · 27.6% of protein
Raw tokenPAS_4:23:0.00000000122:131:115:110
2 HisKA#2
140-209 aa · 70 aa · 17.7% of protein
Raw tokenHisKA:140:0.00000000000000173:209:70:64
3 HATPase_c#3
256-366 aa · 111 aa · 28.1% of protein
Raw tokenHATPase_c:256:2.82e-28:366:111:109
  • Raw architecture: PAS_4:23:0.00000000122:131:115:110#HisKA:140:0.00000000000000173:209:70:64#HATPase_c:256:2.82e-28:366:111:109
  • Domain description: 1 PAS_4,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_033239845::NZ_BTCZ01000068.1::G00037
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1-1188Genomic interval covered by the local TCS group.
Identifiers
Old locus tagJSCD2_22420RefSeq proteinWP_317911267.1
Context group IDGCF_033239845::NZ_BTCZ01000068.1::G00037
Context members
SBI57_RS11285
Partner locus tags
SBI57_RS11285
Partner old locus tags
JSCD2_22420
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_317911267.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagSBI57_RS11285Primary locus identifier stored in the genes table.
Old locus tagJSCD2_22420Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_BTCZ01000068.1Sequence record reported by the local genomic context database.
Genomic interval1-1 188 nt1 188 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1-1 188 ntGCF_033239845::NZ_BTCZ01000068.1::G00037

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_033239845::NZ_BTCZ01000068.1::G00037

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BTCZ01000068.1All displayed genes belong to this local TCS context.
Neighborhood span1-1 188 nt1 188 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt1 188 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0977609Run 6 · HK · 24 sequences
Representative sequenceGCF_000155065#QAE_RS0207840Use this link to inspect the representative gene detail.
PFAM architecturePAS_4 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0977609

Simplified PFAM architecture for HKOC_0977609

PFAM domain coverage: 290 / 618 aa (46.9%)

1 aa618 aa
PAS_4: 246-354 aaPAS_4HisKA: 363-432 aaHisKAHATPase_c: 479-589 aaHATPase_c
PAS_4HisKAHATPase_c
  • Simplified architecture: PAS_4 + HisKA + HATPase_c
  • Raw architecture: PAS_4[246-354] | HisKA[363-432] | HATPase_c[479-589]
  • Domain count: 3
  • Matched identifier: HKOC_0977609
  • Positioned domains: PAS_4 246-354 ; HisKA 363-432 ; HATPase_c 479-589
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0207840

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_033239845
AssemblyASM3323984v1 · Contighaploid
Genome composition4 013 641 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 96 · HK 47 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key