Gene detail

E7C61_RS10435

Histidine kinase, Classic

Clostridium sp. · GCF_032501725

ClassHKTypeClassicLength905 aaTM0ValidatedNoCompleteYesContexttetrad
Gene IDGCF_032501725#E7C61_RS10435Stable P2CS identifier used across views.
GenomeGCF_032501725Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Selected clusterHKOC_0399692Run 6 · 18 sequences · id 100% · cov 80%
External referencesWP_316090129.1 · MIST4 E7C61_RS10435RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

KdpDGAF_3HisKAHATPase_c
Protein length905 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage491 / 905 aa (54.3%)Merged over positioned domains only.
Domain description1 KdpD,1 GAF_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa905 aa
KdpD: 23-232 aa (210 aa)1GAF_3: 546-650 aa (105 aa)2HisKA: 671-736 aa (66 aa)3HATPase_c: 781-890 aa (110 aa)4
Domain-by-domain annotation4 items
1 KdpD#1
23-232 aa · 210 aa · 23.2% of protein
Raw tokenKdpD:23:1.57e-137:232:210:210
2 GAF_3#2
546-650 aa · 105 aa · 11.6% of protein
Raw tokenGAF_3:546:0.0000000238:650:109:129
3 HisKA#3
671-736 aa · 66 aa · 7.3% of protein
Raw tokenHisKA:671:0.00000000000472:736:66:64
4 HATPase_c#4
781-890 aa · 110 aa · 12.2% of protein
Raw tokenHATPase_c:781:4.59e-27:890:111:109
  • Raw architecture: KdpD:23:1.57e-137:232:210:210#GAF_3:546:0.0000000238:650:109:129#HisKA:671:0.00000000000472:736:66:64#HATPase_c:781:4.59e-27:890:111:109
  • Domain description: 1 KdpD,1 GAF_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labeltetradGCF_032501725::NZ_JAWEQK010000007.1::G00019
Group size44 locus tags listed below.
HK / RR2 / 2Counts resolved for the local TCS neighborhood.
Context span117120-123024Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE7C61_10430RefSeq proteinWP_316090129.1
Context group IDGCF_032501725::NZ_JAWEQK010000007.1::G00019
Context members
E7C61_RS10435E7C61_RS10440E7C61_RS10445E7C61_RS10450
Partner locus tags
E7C61_RS10435E7C61_RS10440E7C61_RS10445E7C61_RS10450
Partner old locus tags
E7C61_10430E7C61_10435E7C61_10440E7C61_10445

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_316090129.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE7C61_RS10435Primary locus identifier stored in the genes table.
Old locus tagE7C61_10430Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAWEQK010000007.1Sequence record reported by the local genomic context database.
Genomic interval117 120-119 837 nt2 718 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span117 120-123 024 ntGCF_032501725::NZ_JAWEQK010000007.1::G00019

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_032501725::NZ_JAWEQK010000007.1::G00019

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labeltetradNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAWEQK010000007.1All displayed genes belong to this local TCS context.
Neighborhood span117 120-123 024 nt5 905 nt
Members41 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
117 120 nt123 024 nt
Neighborhood gene cards

4 genes in the current local neighborhood.

E7C61_RS10435GCF_032501725#E7C61_RS10435
HKClassicCurrent focus

117 120-119 837 nt · Forward (+)

Old locus E7C61_10430RefSeq WP_316090129.1
E7C61_RS10440GCF_032501725#E7C61_RS10440
RROmpR

119 806-120 498 nt · Forward (+)

Old locus E7C61_10435RefSeq WP_081663676.1
E7C61_RS10445GCF_032501725#E7C61_RS10445
HKClassic

120 519-122 384 nt · Forward (+)

Old locus E7C61_10440RefSeq WP_051195978.1
E7C61_RS10450GCF_032501725#E7C61_RS10450
RRunclassified

122 362-123 024 nt · Forward (+)

Old locus E7C61_10445RefSeq WP_027098533.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0399692Run 6 · HK · 18 sequences
Representative sequenceGCF_032476635#E6794_RS11305Use this link to inspect the representative gene detail.
PFAM architectureKdpD + DUF4118 + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0399692

Simplified PFAM architecture for HKOC_0399692

PFAM domain coverage: 490 / 905 aa (54.1%)

1 aa905 aa
KdpD: 23-232 aaKdpDDUF4118: 401-504 aaDUF4118HisKA: 671-736 aaHisKAHATPase_c: 781-890 aaHATPase_c
KdpDDUF4118HisKAHATPase_c
  • Simplified architecture: KdpD + DUF4118 + HisKA + HATPase_c
  • Raw architecture: KdpD[23-232] | DUF4118[401-504] | HisKA[671-736] | HATPase_c[781-890]
  • Domain count: 4
  • Matched identifier: HKOC_0399692
  • Positioned domains: KdpD 23-232 ; DUF4118 401-504 ; HisKA 671-736 ; HATPase_c 781-890
Cluster members and taxonomy
Visualization

Representative gene: GCF_032476635#E6794_RS11305

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 506 · GCF_032501725
AssemblyASM3250172v1 · Contighaploid
Genome composition3 545 834 bp · 29,5% GCClostridium sp.
Signal transduction countsGenes 72 · HK 38 · RR 32CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium

Related genes

Preview from the same derived genome key