Gene detail

E6726_RS01395

Histidine kinase, CheA

Clostridium sp. · GCF_032477955

ClassHKTypeCheALength661 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_032477955#E6726_RS01395Stable P2CS identifier used across views.
GenomeGCF_032477955Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Selected clusterHKOC_0869895Run 6 · 10 sequences · id 100% · cov 80%
External referencesWP_027099485.1 · A0A1B8RTQ6 · MIST4 E6726_RS01395RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HptH-kinase_dimHATPase_cCheW
Protein length661 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage416 / 661 aa (62.9%)Merged over positioned domains only.
Domain description1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheWSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa661 aa
Hpt: 5-98 aa (94 aa)1H-kinase_dim: 289-348 aa (60 aa)2HATPase_c: 396-531 aa (136 aa)3CheW: 536-661 aa (126 aa)4
Domain-by-domain annotation4 items
1 Hpt#1
5-98 aa · 94 aa · 14.2% of protein
Raw tokenHpt:5:1.45e-19:98:94:84
2 H-kinase_dim#2
289-348 aa · 60 aa · 9.1% of protein
Raw tokenH-kinase_dim:289:5.06e-16:348:67:67
3 HATPase_c#3
396-531 aa · 136 aa · 20.6% of protein
Raw tokenHATPase_c:396:0.00000000000000496:531:136:109
4 CheW#4
536-661 aa · 126 aa · 19.1% of protein
Raw tokenCheW:536:1.4e-26:661:134:138
  • Raw architecture: Hpt:5:1.45e-19:98:94:84#H-kinase_dim:289:5.06e-16:348:67:67#HATPase_c:396:0.00000000000000496:531:136:109#CheW:536:1.4e-26:661:134:138
  • Domain description: 1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheW
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_032477955::NZ_JAWDVV010000001.1::G00004
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span266791-268776Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE6726_01395RefSeq proteinWP_027099485.1
Context group IDGCF_032477955::NZ_JAWDVV010000001.1::G00004
Context members
E6726_RS01395
Partner locus tags
E6726_RS01395
Partner old locus tags
E6726_01395
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_027099485.1Primary protein accession used for annex mappings.
UniProt accessionA0A1B8RTQ6Primary UniProt accession resolved in the annex database.
UniProt IDA0A1B8RTQ6_9CLOTDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE6726_RS01395Primary locus identifier stored in the genes table.
Old locus tagE6726_01395Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAWDVV010000001.1Sequence record reported by the local genomic context database.
Genomic interval266 791-268 776 nt1 986 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span266 791-268 776 ntGCF_032477955::NZ_JAWDVV010000001.1::G00004

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_032477955::NZ_JAWDVV010000001.1::G00004

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAWDVV010000001.1All displayed genes belong to this local TCS context.
Neighborhood span266 791-268 776 nt1 986 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
266 791 nt268 776 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

E6726_RS01395GCF_032477955#E6726_RS01395
HKCheACurrent focus

266 791-268 776 nt · Forward (+)

Old locus E6726_01395RefSeq WP_027099485.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0869895Run 6 · HK · 10 sequences
Representative sequenceGCF_000424025#G594_RS0116130Use this link to inspect the representative gene detail.
PFAM architectureHpt + P2 + H-kinase_dim + HATPase_c + CheW5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0869895

Simplified PFAM architecture for HKOC_0869895

PFAM domain coverage: 491 / 661 aa (74.3%)

1 aa661 aa
Hpt: 5-97 aaHptP2: 170-246 aaP2H-kinase_dim: 289-348 aaH-kinase_dimHATPase_c: 397-531 aaHATPase_cCheW: 536-661 aaCheW
HptP2H-kinase_dimHATPase_cCheW
  • Simplified architecture: Hpt + P2 + H-kinase_dim + HATPase_c + CheW
  • Raw architecture: Hpt[5-97] | P2[170-246] | H-kinase_dim[289-348] | HATPase_c[397-531] | CheW[536-661]
  • Domain count: 5
  • Matched identifier: HKOC_0869895
  • Positioned domains: Hpt 5-97 ; P2 170-246 ; H-kinase_dim 289-348 ; HATPase_c 397-531 ; CheW 536-661
Cluster members and taxonomy
Visualization

Representative gene: GCF_000424025#G594_RS0116130

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 506 · GCF_032477955
AssemblyASM3247795v1 · Contighaploid
Genome composition3 588 197 bp · 30,0% GCClostridium sp.
Signal transduction countsGenes 71 · HK 37 · RR 32CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium

Related genes

Preview from the same derived genome key