Gene detail

E6784_RS11975

Histidine kinase, Classic

Clostridium sp. · GCF_032476815

ClassHKTypeClassicLength558 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_032476815#E6784_RS11975Stable P2CS identifier used across views.
GenomeGCF_032476815Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Selected clusterHKOC_1264925Run 6 · 70 sequences · id 100% · cov 80%
External referencesWP_027097465.1 · A0A174C5U5 · MIST4 E6784_RS11975RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPPAS_8HisKAHATPase_c
Protein length558 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage303 / 558 aa (54.3%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS_8,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa558 aa
HAMP: 153-221 aa (69 aa)1PAS_8: 231-291 aa (61 aa)2HisKA: 340-404 aa (65 aa)3HATPase_c: 449-556 aa (108 aa)4
Domain-by-domain annotation4 items
1 HAMP#1
153-221 aa · 69 aa · 12.4% of protein
Raw tokenHAMP:153:7.51e-17:221:69:69
2 PAS_8#2
231-291 aa · 61 aa · 10.9% of protein
Raw tokenPAS_8:231:0.00000176:291:61:65
3 HisKA#3
340-404 aa · 65 aa · 11.6% of protein
Raw tokenHisKA:340:4.88e-23:404:65:64
4 HATPase_c#4
449-556 aa · 108 aa · 19.4% of protein
Raw tokenHATPase_c:449:2.48e-30:556:108:109
  • Raw architecture: HAMP:153:7.51e-17:221:69:69#PAS_8:231:0.00000176:291:61:65#HisKA:340:4.88e-23:404:65:64#HATPase_c:449:2.48e-30:556:108:109
  • Domain description: 1 HAMP,1 PAS_8,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_032476815::NZ_JAWDYB010000008.1::G00025
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span122638-125014Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE6784_11975RefSeq proteinWP_027097465.1
Context group IDGCF_032476815::NZ_JAWDYB010000008.1::G00025
Context members
E6784_RS11975E6784_RS11980
Partner locus tags
E6784_RS11975E6784_RS11980
Partner old locus tags
E6784_11975E6784_11980
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_027097465.1Primary protein accession used for annex mappings.
UniProt accessionA0A174C5U5Primary UniProt accession resolved in the annex database.
UniProt IDA0A174C5U5_9CLOTDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE6784_RS11975Primary locus identifier stored in the genes table.
Old locus tagE6784_11975Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAWDYB010000008.1Sequence record reported by the local genomic context database.
Genomic interval122 638-124 314 nt1 677 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span122 638-125 014 ntGCF_032476815::NZ_JAWDYB010000008.1::G00025

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_032476815::NZ_JAWDYB010000008.1::G00025

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAWDYB010000008.1All displayed genes belong to this local TCS context.
Neighborhood span122 638-125 014 nt2 377 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
122 638 nt125 014 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E6784_RS11975GCF_032476815#E6784_RS11975
HKClassicCurrent focus

122 638-124 314 nt · Reverse (-)

Old locus E6784_11975RefSeq WP_027097465.1
E6784_RS11980GCF_032476815#E6784_RS11980
RROmpR

124 316-125 014 nt · Reverse (-)

Old locus E6784_11980RefSeq WP_027097464.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1264925Run 6 · HK · 70 sequences
Representative sequenceGCF_000424025#G594_RS0104430Use this link to inspect the representative gene detail.
PFAM architectureHAMP + PAS_8 + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1264925

Simplified PFAM architecture for HKOC_1264925

PFAM domain coverage: 282 / 558 aa (50.5%)

1 aa558 aa
HAMP: 170-221 aaHAMPPAS_8: 231-287 aaPAS_8HisKA: 340-404 aaHisKAHATPase_c: 449-556 aaHATPase_c
HAMPPAS_8HisKAHATPase_c
  • Simplified architecture: HAMP + PAS_8 + HisKA + HATPase_c
  • Raw architecture: HAMP[170-221] | PAS_8[231-287] | HisKA[340-404] | HATPase_c[449-556]
  • Domain count: 4
  • Matched identifier: HKOC_1264925
  • Positioned domains: HAMP 170-221 ; PAS_8 231-287 ; HisKA 340-404 ; HATPase_c 449-556
Cluster members and taxonomy
Visualization

Representative gene: GCF_000424025#G594_RS0104430

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 506 · GCF_032476815
AssemblyASM3247681v1 · Contighaploid
Genome composition3 848 194 bp · 30,0% GCClostridium sp.
Signal transduction countsGenes 74 · HK 38 · RR 34CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium

Related genes

Preview from the same derived genome key