Gene detail

E7A11_RS10910

Histidine kinase, Classic

Clostridium sp. · GCF_032472255

ClassHKTypeClassicLength594 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_032472255#E7A11_RS10910Stable P2CS identifier used across views.
GenomeGCF_032472255Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Selected clusterHKOC_1087267Run 6 · 73 sequences · id 100% · cov 80%
External referencesWP_027097132.1 · A0A174USY8 · MIST4 E7A11_RS10910RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length594 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage409 / 594 aa (68.9%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa594 aa
dCache_1: 124-278 aa (155 aa)1HAMP: 295-363 aa (69 aa)2His_kinase: 379-458 aa (80 aa)3HATPase_c: 474-578 aa (105 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
124-278 aa · 155 aa · 26.1% of protein
Raw tokendCache_1:124:9.35e-17:278:159:195
2 HAMP#2
295-363 aa · 69 aa · 11.6% of protein
Raw tokenHAMP:295:0.0000000048:363:69:69
3 His_kinase#3
379-458 aa · 80 aa · 13.5% of protein
Raw tokenHis_kinase:379:1.83e-34:458:80:80
4 HATPase_c#4
474-578 aa · 105 aa · 17.7% of protein
Raw tokenHATPase_c:474:3.56e-17:578:109:109
  • Raw architecture: dCache_1:124:9.35e-17:278:159:195#HAMP:295:0.0000000048:363:69:69#His_kinase:379:1.83e-34:458:80:80#HATPase_c:474:3.56e-17:578:109:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_032472255::NZ_JAWEGU010000013.1::G00026
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span63081-66473Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE7A11_10915RefSeq proteinWP_027097132.1
Context group IDGCF_032472255::NZ_JAWEGU010000013.1::G00026
Context members
E7A11_RS10905E7A11_RS10910
Partner locus tags
E7A11_RS10905E7A11_RS10910
Partner old locus tags
E7A11_10910E7A11_10915
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_027097132.1Primary protein accession used for annex mappings.
UniProt accessionA0A174USY8Primary UniProt accession resolved in the annex database.
UniProt IDA0A174USY8_9CLOTDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE7A11_RS10910Primary locus identifier stored in the genes table.
Old locus tagE7A11_10915Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAWEGU010000013.1Sequence record reported by the local genomic context database.
Genomic interval64 689-66 473 nt1 785 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span63 081-66 473 ntGCF_032472255::NZ_JAWEGU010000013.1::G00026

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_032472255::NZ_JAWEGU010000013.1::G00026

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAWEGU010000013.1All displayed genes belong to this local TCS context.
Neighborhood span63 081-66 473 nt3 393 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
63 081 nt66 473 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E7A11_RS10905GCF_032472255#E7A11_RS10905
RRunclassified

63 081-64 679 nt · Forward (+)

Old locus E7A11_10910RefSeq WP_027097133.1
E7A11_RS10910GCF_032472255#E7A11_RS10910
HKClassicCurrent focus

64 689-66 473 nt · Forward (+)

Old locus E7A11_10915RefSeq WP_027097132.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1087267Run 6 · HK · 73 sequences
Representative sequenceGCF_000424025#G594_RS0102585Use this link to inspect the representative gene detail.
PFAM architecturedCache_1 + HAMP + His_kinase + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1087267

Simplified PFAM architecture for HKOC_1087267

PFAM domain coverage: 467 / 594 aa (78.6%)

1 aa594 aa
dCache_1: 45-277 aadCache_1HAMP: 313-361 aaHAMPHis_kinase: 380-458 aaHis_kinaseHATPase_c: 474-579 aaHATPase_c
dCache_1HAMPHis_kinaseHATPase_c
  • Simplified architecture: dCache_1 + HAMP + His_kinase + HATPase_c
  • Raw architecture: dCache_1[45-277] | HAMP[313-361] | His_kinase[380-458] | HATPase_c[474-579]
  • Domain count: 4
  • Matched identifier: HKOC_1087267
  • Positioned domains: dCache_1 45-277 ; HAMP 313-361 ; His_kinase 380-458 ; HATPase_c 474-579
Cluster members and taxonomy
Visualization

Representative gene: GCF_000424025#G594_RS0102585

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 506 · GCF_032472255
AssemblyASM3247225v1 · Contighaploid
Genome composition3 714 237 bp · 29,5% GCClostridium sp.
Signal transduction countsGenes 74 · HK 39 · RR 33CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium

Related genes

Preview from the same derived genome key