Gene detail

E7A11_RS05835

Histidine kinase, Classic

Clostridium sp. · GCF_032472255

ClassHKTypeClassicLength905 aaTM0ValidatedNoCompleteYesContexttetrad
Gene IDGCF_032472255#E7A11_RS05835Stable P2CS identifier used across views.
GenomeGCF_032472255Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Selected clusterHKOC_0398644Run 6 · 13 sequences · id 100% · cov 80%
External referencesWP_055254748.1 · A0A174GJS2 · MIST4 E7A11_RS05835RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

KdpDGAF_3HisKAHATPase_c
Protein length905 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage491 / 905 aa (54.3%)Merged over positioned domains only.
Domain description1 KdpD,1 GAF_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa905 aa
KdpD: 23-232 aa (210 aa)1GAF_3: 546-650 aa (105 aa)2HisKA: 671-736 aa (66 aa)3HATPase_c: 781-890 aa (110 aa)4
Domain-by-domain annotation4 items
1 KdpD#1
23-232 aa · 210 aa · 23.2% of protein
Raw tokenKdpD:23:1.54e-137:232:210:210
2 GAF_3#2
546-650 aa · 105 aa · 11.6% of protein
Raw tokenGAF_3:546:0.0000000232:650:109:129
3 HisKA#3
671-736 aa · 66 aa · 7.3% of protein
Raw tokenHisKA:671:0.0000000000043:736:66:64
4 HATPase_c#4
781-890 aa · 110 aa · 12.2% of protein
Raw tokenHATPase_c:781:7.16e-27:890:111:109
  • Raw architecture: KdpD:23:1.54e-137:232:210:210#GAF_3:546:0.0000000232:650:109:129#HisKA:671:0.0000000000043:736:66:64#HATPase_c:781:7.16e-27:890:111:109
  • Domain description: 1 KdpD,1 GAF_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labeltetradGCF_032472255::NZ_JAWEGU010000006.1::G00019
Group size44 locus tags listed below.
HK / RR2 / 2Counts resolved for the local TCS neighborhood.
Context span33920-39824Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE7A11_05840RefSeq proteinWP_055254748.1
Context group IDGCF_032472255::NZ_JAWEGU010000006.1::G00019
Context members
E7A11_RS05820E7A11_RS05825E7A11_RS05830E7A11_RS05835
Partner locus tags
E7A11_RS05820E7A11_RS05825E7A11_RS05830E7A11_RS05835
Partner old locus tags
E7A11_05825E7A11_05830E7A11_05835E7A11_05840

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_055254748.1Primary protein accession used for annex mappings.
UniProt accessionA0A174GJS2Primary UniProt accession resolved in the annex database.
UniProt IDA0A174GJS2_9CLOTDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE7A11_RS05835Primary locus identifier stored in the genes table.
Old locus tagE7A11_05840Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAWEGU010000006.1Sequence record reported by the local genomic context database.
Genomic interval37 107-39 824 nt2 718 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span33 920-39 824 ntGCF_032472255::NZ_JAWEGU010000006.1::G00019

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_032472255::NZ_JAWEGU010000006.1::G00019

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labeltetradNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAWEGU010000006.1All displayed genes belong to this local TCS context.
Neighborhood span33 920-39 824 nt5 905 nt
Members41 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
33 920 nt39 824 nt
Neighborhood gene cards

4 genes in the current local neighborhood.

E7A11_RS05820GCF_032472255#E7A11_RS05820
RRunclassified

33 920-34 582 nt · Reverse (-)

Old locus E7A11_05825RefSeq WP_027098533.1
E7A11_RS05825GCF_032472255#E7A11_RS05825
HKClassic

34 560-36 425 nt · Reverse (-)

Old locus E7A11_05830RefSeq WP_055254746.1
E7A11_RS05830GCF_032472255#E7A11_RS05830
RROmpR

36 446-37 138 nt · Reverse (-)

Old locus E7A11_05835RefSeq WP_081663676.1
E7A11_RS05835GCF_032472255#E7A11_RS05835
HKClassicCurrent focus

37 107-39 824 nt · Reverse (-)

Old locus E7A11_05840RefSeq WP_055254748.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0398644Run 6 · HK · 13 sequences
Representative sequenceGCF_001404795#ARB71_RS13560Use this link to inspect the representative gene detail.
PFAM architectureKdpD + DUF4118 + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0398644

Simplified PFAM architecture for HKOC_0398644

PFAM domain coverage: 490 / 905 aa (54.1%)

1 aa905 aa
KdpD: 23-232 aaKdpDDUF4118: 401-504 aaDUF4118HisKA: 671-736 aaHisKAHATPase_c: 781-890 aaHATPase_c
KdpDDUF4118HisKAHATPase_c
  • Simplified architecture: KdpD + DUF4118 + HisKA + HATPase_c
  • Raw architecture: KdpD[23-232] | DUF4118[401-504] | HisKA[671-736] | HATPase_c[781-890]
  • Domain count: 4
  • Matched identifier: HKOC_0398644
  • Positioned domains: KdpD 23-232 ; DUF4118 401-504 ; HisKA 671-736 ; HATPase_c 781-890
Cluster members and taxonomy
Visualization

Representative gene: GCF_001404795#ARB71_RS13560

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 506 · GCF_032472255
AssemblyASM3247225v1 · Contighaploid
Genome composition3 714 237 bp · 29,5% GCClostridium sp.
Signal transduction countsGenes 74 · HK 39 · RR 33CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium

Related genes

Preview from the same derived genome key