Gene detail

XC43_RS10540

Histidine kinase, Classic

Clostridioides difficile · GCF_032081585

ClassHKTypeClassicLength389 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_032081585#XC43_RS10540Stable P2CS identifier used across views.
GenomeGCF_032081585Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1674775Run 6 · 28 sequences · id 100% · cov 80%
External referencesWP_021419284.1 · MIST4 XC43_RS10540RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length389 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 389 aa (64.5%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for XC43_RS10540
Domain-by-domain annotation3 items
1 HAMP#1
76-153 aa · 78 aa · 20.1% of protein
Raw tokenHAMP:76:0.00000000565:153:78:69
2 HisKA#2
165-230 aa · 66 aa · 17.0% of protein
Raw tokenHisKA:165:0.000000000887:230:66:64
3 HATPase_c#3
280-386 aa · 107 aa · 27.5% of protein
Raw tokenHATPase_c:280:9.86e-27:386:107:109
  • Raw architecture: HAMP:76:0.00000000565:153:78:69#HisKA:165:0.000000000887:230:66:64#HATPase_c:280:9.86e-27:386:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_032081585::NZ_LIFE01000048.1::G00027
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span16325-18460Genomic interval covered by the local TCS group.
Identifiers
Old locus tagXC43_10480RefSeq proteinWP_021419284.1
Context group IDGCF_032081585::NZ_LIFE01000048.1::G00027
Context members
XC43_RS10540XC43_RS10545
Partner locus tags
XC43_RS10540XC43_RS10545
Partner old locus tags
XC43_10480XC43_10485
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021419284.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagXC43_RS10540Primary locus identifier stored in the genes table.
Old locus tagXC43_10480Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_LIFE01000048.1Sequence record reported by the local genomic context database.
Genomic interval16 325-17 494 nt1 170 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span16 325-18 460 ntGCF_032081585::NZ_LIFE01000048.1::G00027

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_032081585::NZ_LIFE01000048.1::G00027

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_LIFE01000048.1All displayed genes belong to this local TCS context.
Neighborhood span16 325-18 460 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
16 325 nt18 460 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

XC43_RS10540GCF_032081585#XC43_RS10540
HKClassicCurrent focus

16 325-17 494 nt · Reverse (-)

Old locus XC43_10480RefSeq WP_021419284.1
XC43_RS10545GCF_032081585#XC43_RS10545
RROmpR

17 768-18 460 nt · Reverse (-)

Old locus XC43_10485RefSeq WP_003434748.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1674775Run 6 · HK · 28 sequences
Representative sequenceGCF_000450145#QK3_RS02580Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1674775

Simplified PFAM architecture for HKOC_1674775

PFAM domain coverage: 223 / 474 aa (47.0%)

1 aa474 aa
HAMP: 188-238 aaHAMPHisKA: 251-315 aaHisKAHATPase_c: 365-471 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[188-238] | HisKA[251-315] | HATPase_c[365-471]
  • Domain count: 3
  • Matched identifier: HKOC_1674775
  • Positioned domains: HAMP 188-238 ; HisKA 251-315 ; HATPase_c 365-471
Cluster members and taxonomy
Visualization

Representative gene: GCF_000450145#QK3_RS02580

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_032081585
AssemblyASM3208158v1 · Scaffoldhaploid
Genome composition4 288 335 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 107 · HK 52 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key