Gene detail

XC42_RS02610

Histidine kinase, Classic

Clostridioides difficile · GCF_032081565

ClassHKTypeClassicLength387 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_032081565#XC42_RS02610Stable P2CS identifier used across views.
GenomeGCF_032081565Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2550063Run 6 · 984 sequences · id 100% · cov 80%
External referencesWP_009896183.1 · Q18BD5 · MIST4 XC42_RS02610RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_3HATPase_c
Protein length387 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage151 / 387 aa (39.0%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for XC42_RS02610
Domain-by-domain annotation2 items
1 HisKA_3#1
188-253 aa · 66 aa · 17.1% of protein
Raw tokenHisKA_3:188:4.07e-20:253:67:68
2 HATPase_c#2
294-378 aa · 85 aa · 22.0% of protein
Raw tokenHATPase_c:294:0.00000000019:378:104:109
  • Raw architecture: HisKA_3:188:4.07e-20:253:67:68#HATPase_c:294:0.00000000019:378:104:109
  • Domain description: 1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_032081565::NZ_LIFD01000005.1::G00006
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span188547-190350Genomic interval covered by the local TCS group.
Identifiers
Old locus tagXC42_02520RefSeq proteinWP_009896183.1
Context group IDGCF_032081565::NZ_LIFD01000005.1::G00006
Context members
XC42_RS02605XC42_RS02610
Partner locus tags
XC42_RS02605XC42_RS02610
Partner old locus tags
XC42_02515XC42_02520
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009896183.1Primary protein accession used for annex mappings.
UniProt accessionQ18BD5Primary UniProt accession resolved in the annex database.
UniProt IDQ18BD5_CLOD6Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagXC42_RS02610Primary locus identifier stored in the genes table.
Old locus tagXC42_02520Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_LIFD01000005.1Sequence record reported by the local genomic context database.
Genomic interval189 187-190 350 nt1 164 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span188 547-190 350 ntGCF_032081565::NZ_LIFD01000005.1::G00006

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_032081565::NZ_LIFD01000005.1::G00006

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_LIFD01000005.1All displayed genes belong to this local TCS context.
Neighborhood span188 547-190 350 nt1 804 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
188 547 nt190 350 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

XC42_RS02605GCF_032081565#XC42_RS02605
RRNarL

188 547-189 194 nt · Reverse (-)

Old locus XC42_02515RefSeq WP_009896181.1
XC42_RS02610GCF_032081565#XC42_RS02610
HKClassicCurrent focus

189 187-190 350 nt · Reverse (-)

Old locus XC42_02520RefSeq WP_009896183.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2550063Run 6 · HK · 984 sequences
Representative sequenceGCF_000009205#CD630_RS07055Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2550063

Simplified PFAM architecture for HKOC_2550063

PFAM domain coverage: 150 / 387 aa (38.8%)

1 aa387 aa
HisKA_3: 188-252 aaHisKA_3HATPase_c: 294-378 aaHATPase_c
HisKA_3HATPase_c
  • Simplified architecture: HisKA_3 + HATPase_c
  • Raw architecture: HisKA_3[188-252] | HATPase_c[294-378]
  • Domain count: 2
  • Matched identifier: HKOC_2550063
  • Positioned domains: HisKA_3 188-252 ; HATPase_c 294-378
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS07055

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_032081565
AssemblyASM3208156v1 · Scaffoldhaploid
Genome composition4 343 635 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 47 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key