Gene detail

XC24_RS12700

Histidine kinase, Classic

Clostridioides difficile · GCF_032081185

ClassHKTypeClassicLength618 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_032081185#XC24_RS12700Stable P2CS identifier used across views.
GenomeGCF_032081185Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0977572Run 6 · 356 sequences · id 100% · cov 80%
External referencesWP_009893166.1 · A0A0H3N345 · MIST4 XC24_RS12700RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_4HisKAHATPase_c
Protein length618 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage290 / 618 aa (46.9%)Merged over positioned domains only.
Domain description1 PAS_4,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa618 aa
PAS_4: 246-354 aa (109 aa)1HisKA: 363-432 aa (70 aa)2HATPase_c: 479-589 aa (111 aa)3
Domain-by-domain annotation3 items
1 PAS_4#1
246-354 aa · 109 aa · 17.6% of protein
Raw tokenPAS_4:246:0.0000000000267:354:115:110
2 HisKA#2
363-432 aa · 70 aa · 11.3% of protein
Raw tokenHisKA:363:0.0000000000000012:432:70:64
3 HATPase_c#3
479-589 aa · 111 aa · 18.0% of protein
Raw tokenHATPase_c:479:1.19e-27:589:111:109
  • Raw architecture: PAS_4:246:0.0000000000267:354:115:110#HisKA:363:0.0000000000000012:432:70:64#HATPase_c:479:1.19e-27:589:111:109
  • Domain description: 1 PAS_4,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_032081185::NZ_LIEL01000131.1::G00029
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span46888-48744Genomic interval covered by the local TCS group.
Identifiers
Old locus tagXC24_12705RefSeq proteinWP_009893166.1
Context group IDGCF_032081185::NZ_LIEL01000131.1::G00029
Context members
XC24_RS12700
Partner locus tags
XC24_RS12700
Partner old locus tags
XC24_12705
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009893166.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N345Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N345_CLODCDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagXC24_RS12700Primary locus identifier stored in the genes table.
Old locus tagXC24_12705Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_LIEL01000131.1Sequence record reported by the local genomic context database.
Genomic interval46 888-48 744 nt1 857 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span46 888-48 744 ntGCF_032081185::NZ_LIEL01000131.1::G00029

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_032081185::NZ_LIEL01000131.1::G00029

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_LIEL01000131.1All displayed genes belong to this local TCS context.
Neighborhood span46 888-48 744 nt1 857 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
46 888 nt48 744 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

XC24_RS12700GCF_032081185#XC24_RS12700
HKClassicCurrent focus

46 888-48 744 nt · Reverse (-)

Old locus XC24_12705RefSeq WP_009893166.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0977572Run 6 · HK · 356 sequences
Representative sequenceGCF_000003215#QAC_RS0208160Use this link to inspect the representative gene detail.
PFAM architecturePAS_4 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0977572

Simplified PFAM architecture for HKOC_0977572

PFAM domain coverage: 290 / 618 aa (46.9%)

1 aa618 aa
PAS_4: 246-354 aaPAS_4HisKA: 363-432 aaHisKAHATPase_c: 479-589 aaHATPase_c
PAS_4HisKAHATPase_c
  • Simplified architecture: PAS_4 + HisKA + HATPase_c
  • Raw architecture: PAS_4[246-354] | HisKA[363-432] | HATPase_c[479-589]
  • Domain count: 3
  • Matched identifier: HKOC_0977572
  • Positioned domains: PAS_4 246-354 ; HisKA 363-432 ; HATPase_c 479-589
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0208160

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_032081185
AssemblyASM3208118v1 · Scaffoldhaploid
Genome composition4 376 926 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 113 · HK 53 · RR 58CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key