Gene detail

RJP78_RS01035

Histidine kinase, Unorthodox

Escherichia coli · GCF_031628475

ClassHKTypeUnorthodoxLength1403 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_031628475#RJP78_RS01035Stable P2CS identifier used across views.
GenomeGCF_031628475Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_0067980Run 6 · 1456 sequences · id 100% · cov 80% · representative
External referencesWP_310945431.1 · MIST4 RJP78_RS01035RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regGerEPBPbHisKAHATPase_cHpt
Protein length1403 aaLength used to scale native and Biotite-like views.
Annotated domains88 with usable coordinates.
Domain coverage964 / 1403 aa (68.7%)Merged over positioned domains only.
Domain description2 Response_reg,1 GerE,2 PBPb,1 HisKA,1 HATPase_c,1 HptSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa1403 aa
Response_reg: 4-114 aa (111 aa)1GerE: 142-198 aa (57 aa)2PBPb: 279-482 aa (204 aa)3PBPb: 510-725 aa (216 aa)4HisKA: 917-983 aa (67 aa)5HATPase_c: 1031-1144 aa (114 aa)6Response_reg: 1167-1276 aa (110 aa)7Hpt: 1310-1394 aa (85 aa)8
Domain-by-domain annotation8 items
1 Response_reg#1
4-114 aa · 111 aa · 7.9% of protein
Raw tokenResponse_reg:4:7.33e-33:114:111:111
2 GerE#2
142-198 aa · 57 aa · 4.1% of protein
Raw tokenGerE:142:6.02e-21:198:57:57
3 PBPb#3
279-482 aa · 204 aa · 14.5% of protein
Raw tokenPBPb:279:0.00000000000000106:482:209:219
4 PBPb#4
510-725 aa · 216 aa · 15.4% of protein
Raw tokenPBPb:510:5.4e-39:725:223:219
5 HisKA#5
917-983 aa · 67 aa · 4.8% of protein
Raw tokenHisKA:917:2.28e-16:983:67:64
6 HATPase_c#6
1031-1144 aa · 114 aa · 8.1% of protein
Raw tokenHATPase_c:1031:3.37e-32:1144:114:109
7 Response_reg#7
1167-1276 aa · 110 aa · 7.8% of protein
Raw tokenResponse_reg:1167:3.54e-39:1276:110:111
8 Hpt#8
1310-1394 aa · 85 aa · 6.1% of protein
Raw tokenHpt:1310:0.0000000984:1394:85:84
  • Raw architecture: Response_reg:4:7.33e-33:114:111:111#GerE:142:6.02e-21:198:57:57#PBPb:279:0.00000000000000106:482:209:219#PBPb:510:5.4e-39:725:223:219#HisKA:917:2.28e-16:983:67:64#HATPase_c:1031:3.37e-32:1144:114:109#Response_reg:1167:3.54e-39:1276:110:111#Hpt:1310:0.0000000984:1394:85:84
  • Domain description: 2 Response_reg,1 GerE,2 PBPb,1 HisKA,1 HATPase_c,1 Hpt
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_031628475::NZ_JAVKNJ010000001.1::G00005
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span216731-220942Genomic interval covered by the local TCS group.
Identifiers
Old locus tagRJP78_01035RefSeq proteinWP_310945431.1
Context group IDGCF_031628475::NZ_JAVKNJ010000001.1::G00005
Context members
RJP78_RS01035
Partner locus tags
RJP78_RS01035
Partner old locus tags
RJP78_01035
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_310945431.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagRJP78_RS01035Primary locus identifier stored in the genes table.
Old locus tagRJP78_01035Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAVKNJ010000001.1Sequence record reported by the local genomic context database.
Genomic interval216 731-220 942 nt4 212 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span216 731-220 942 ntGCF_031628475::NZ_JAVKNJ010000001.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_031628475::NZ_JAVKNJ010000001.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAVKNJ010000001.1All displayed genes belong to this local TCS context.
Neighborhood span216 731-220 942 nt4 212 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
216 731 nt220 942 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

RJP78_RS01035GCF_031628475#RJP78_RS01035
HKUnorthodoxCurrent focus

216 731-220 942 nt · Reverse (-)

Old locus RJP78_01035RefSeq WP_310945431.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0067980Run 6 · HK · 1456 sequences
Representative sequenceGCF_031628475#RJP78_RS01035The current gene is the representative for this cluster.
PFAM architectureResponse_reg + GerE + SBP_bac_3 + SBP_bac_3 + HisKA + HATPase_c + Response_reg + Hpt8 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0067980

Simplified PFAM architecture for HKOC_0067980

PFAM domain coverage: 971 / 1403 aa (69.2%)

1 aa1403 aa
Response_reg: 4-114 aaResponse_regGerE: 142-198 aaSBP_bac_3: 268-482 aaSBP_bac_3SBP_bac_3: 512-726 aaSBP_bac_3HisKA: 917-983 aaHATPase_c: 1031-1143 aaHATPase_cResponse_reg: 1167-1276 aaResponse_regHpt: 1310-1392 aaHpt
Response_regGerESBP_bac_3SBP_bac_3HisKAHATPase_cResponse_regHpt
  • Simplified architecture: Response_reg + GerE + SBP_bac_3 + SBP_bac_3 + HisKA + HATPase_c + Response_reg + Hpt
  • Raw architecture: Response_reg[4-114] | GerE[142-198] | SBP_bac_3[268-482] | SBP_bac_3[512-726] | HisKA[917-983] | HATPase_c[1031-1143] | Response_reg[1167-1276] | Hpt[1310-1392]
  • Domain count: 8
  • Matched identifier: HKOC_0067980
  • Positioned domains: Response_reg 4-114 ; GerE 142-198 ; SBP_bac_3 268-482 ; SBP_bac_3 512-726 ; HisKA 917-983 ; HATPase_c 1031-1143 ; Response_reg 1167-1276 ; Hpt 1310-1392
Cluster members and taxonomy
Visualization

Representative gene: GCF_031628475#RJP78_RS01035

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 562 · GCF_031628475
AssemblyASM3162847v1 · Contighaploid
Genome composition5 201 656 bp · 50,5% GCEscherichia coli
Signal transduction countsGenes 61 · HK 30 · RR 31CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key