Gene detail

PZH45_RS04455

Histidine kinase, Hybrid

Faecalibacterium prausnitzii · GCF_029076745

ClassHKTypeHybridLength1084 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_029076745#PZH45_RS04455Stable P2CS identifier used across views.
GenomeGCF_029076745Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Faecalibacterium
Selected clusterHKOC_0237373Run 6 · 5 sequences · id 100% · cov 80%
External referencesWP_154265911.1 · A0A844DP87 · MIST4 PZH45_RS04455RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PBPbHisKAHATPase_cResponse_reg
Protein length1084 aaLength used to scale native and Biotite-like views.
Annotated domains66 with usable coordinates.
Domain coverage837 / 1084 aa (77.2%)Merged over positioned domains only.
Domain description2 PBPb,1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa1084 aa
PBPb: 45-262 aa (218 aa)1PBPb: 284-486 aa (203 aa)2HisKA: 573-639 aa (67 aa)3HATPase_c: 687-803 aa (117 aa)4Response_reg: 823-936 aa (114 aa)5Response_reg: 964-1081 aa (118 aa)6
Domain-by-domain annotation6 items
1 PBPb#1
45-262 aa · 218 aa · 20.1% of protein
Raw tokenPBPb:45:1.83e-29:262:231:219
2 PBPb#2
284-486 aa · 203 aa · 18.7% of protein
Raw tokenPBPb:284:0.00000000000000137:486:213:219
3 HisKA#3
573-639 aa · 67 aa · 6.2% of protein
Raw tokenHisKA:573:2.65e-19:639:67:64
4 HATPase_c#4
687-803 aa · 117 aa · 10.8% of protein
Raw tokenHATPase_c:687:2.31e-32:803:117:109
5 Response_reg#5
823-936 aa · 114 aa · 10.5% of protein
Raw tokenResponse_reg:823:6.74e-21:936:114:111
6 Response_reg#6
964-1081 aa · 118 aa · 10.9% of protein
Raw tokenResponse_reg:964:8e-33:1081:118:111
  • Raw architecture: PBPb:45:1.83e-29:262:231:219#PBPb:284:0.00000000000000137:486:213:219#HisKA:573:2.65e-19:639:67:64#HATPase_c:687:2.31e-32:803:117:109#Response_reg:823:6.74e-21:936:114:111#Response_reg:964:8e-33:1081:118:111
  • Domain description: 2 PBPb,1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_029076745::NZ_JARFIQ010000012.1::G00018
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span176-3430Genomic interval covered by the local TCS group.
Identifiers
Old locus tagPZH45_04495RefSeq proteinWP_154265911.1
Context group IDGCF_029076745::NZ_JARFIQ010000012.1::G00018
Context members
PZH45_RS04455
Partner locus tags
PZH45_RS04455
Partner old locus tags
PZH45_04495
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_154265911.1Primary protein accession used for annex mappings.
UniProt accessionA0A844DP87Primary UniProt accession resolved in the annex database.
UniProt IDA0A844DP87_9FIRMDisplay identifier provided by UniProt.
GO / PubMed1 / 1Unique GO terms and literature references available below.
GO terms
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagPZH45_RS04455Primary locus identifier stored in the genes table.
Old locus tagPZH45_04495Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JARFIQ010000012.1Sequence record reported by the local genomic context database.
Genomic interval176-3 430 nt3 255 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span176-3 430 ntGCF_029076745::NZ_JARFIQ010000012.1::G00018

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_029076745::NZ_JARFIQ010000012.1::G00018

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JARFIQ010000012.1All displayed genes belong to this local TCS context.
Neighborhood span176-3 430 nt3 255 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
176 nt3 430 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0237373Run 6 · HK · 5 sequences
Representative sequenceGCF_009680085#GKE10_RS11580Use this link to inspect the representative gene detail.
PFAM architectureSBP_bac_3 + SBP_bac_3 + HisKA + HATPase_c + Response_reg + Response_reg6 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0237373

Simplified PFAM architecture for HKOC_0237373

PFAM domain coverage: 800 / 1084 aa (73.8%)

1 aa1084 aa
SBP_bac_3: 53-249 aaSBP_bac_3SBP_bac_3: 298-486 aaSBP_bac_3HisKA: 573-639 aaHisKAHATPase_c: 687-803 aaHATPase_cResponse_reg: 823-935 aaResponse_regResponse_reg: 964-1080 aaResponse_reg
SBP_bac_3SBP_bac_3HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: SBP_bac_3 + SBP_bac_3 + HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: SBP_bac_3[53-249] | SBP_bac_3[298-486] | HisKA[573-639] | HATPase_c[687-803] | Response_reg[823-935] | Response_reg[964-1080]
  • Domain count: 6
  • Matched identifier: HKOC_0237373
  • Positioned domains: SBP_bac_3 53-249 ; SBP_bac_3 298-486 ; HisKA 573-639 ; HATPase_c 687-803 ; Response_reg 823-935 ; Response_reg 964-1080
Cluster members and taxonomy
Visualization

Representative gene: GCF_009680085#GKE10_RS11580

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 853 · GCF_029076745
AssemblyASM2907674v1 · Contighaploid
Genome composition2 943 763 bp · 56,5% GCFaecalibacterium prausnitzii
Signal transduction countsGenes 56 · HK 27 · RR 28CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusFaecalibacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Faecalibacterium

Related genes

Preview from the same derived genome key