Gene detail

PSL48_RS00580

Histidine kinase, Classic

Clostridioides difficile · GCF_028596735

ClassHKTypeClassicLength530 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_028596735#PSL48_RS00580Stable P2CS identifier used across views.
GenomeGCF_028596735Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1355523Run 6 · 295 sequences · id 100% · cov 80%
External referencesWP_003423136.1 · D5Q2Z1 · MIST4 PSL48_RS00580RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length530 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage153 / 530 aa (28.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for PSL48_RS00580
Domain-by-domain annotation2 items
1 HisKA#1
309-375 aa · 67 aa · 12.6% of protein
Raw tokenHisKA:309:0.000000000000009:375:67:64
2 HATPase_c#2
428-513 aa · 86 aa · 16.2% of protein
Raw tokenHATPase_c:428:0.0000000975:513:90:109
  • Raw architecture: HisKA:309:0.000000000000009:375:67:64#HATPase_c:428:0.0000000975:513:90:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_028596735::NZ_JAQRIS010000001.1::G00011
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span129499-131776Genomic interval covered by the local TCS group.
Identifiers
Old locus tagPSL48_00580RefSeq proteinWP_003423136.1
Context group IDGCF_028596735::NZ_JAQRIS010000001.1::G00011
Context members
PSL48_RS00575PSL48_RS00580
Partner locus tags
PSL48_RS00575PSL48_RS00580
Partner old locus tags
PSL48_00575PSL48_00580
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003423136.1Primary protein accession used for annex mappings.
UniProt accessionD5Q2Z1Primary UniProt accession resolved in the annex database.
UniProt IDD5Q2Z1_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagPSL48_RS00580Primary locus identifier stored in the genes table.
Old locus tagPSL48_00580Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAQRIS010000001.1Sequence record reported by the local genomic context database.
Genomic interval130 184-131 776 nt1 593 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span129 499-131 776 ntGCF_028596735::NZ_JAQRIS010000001.1::G00011

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_028596735::NZ_JAQRIS010000001.1::G00011

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAQRIS010000001.1All displayed genes belong to this local TCS context.
Neighborhood span129 499-131 776 nt2 278 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
129 499 nt131 776 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

PSL48_RS00575GCF_028596735#PSL48_RS00575
RROmpR

129 499-130 215 nt · Forward (+)

Old locus PSL48_00575RefSeq WP_003423137.1
PSL48_RS00580GCF_028596735#PSL48_RS00580
HKClassicCurrent focus

130 184-131 776 nt · Forward (+)

Old locus PSL48_00580RefSeq WP_003423136.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1355523Run 6 · HK · 295 sequences
Representative sequenceGCF_000155065#QAE_RS0211330Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1355523

Simplified PFAM architecture for HKOC_1355523

PFAM domain coverage: 194 / 530 aa (36.6%)

1 aa530 aa
HAMP: 255-297 aaHAMPHisKA: 309-375 aaHisKAHATPase_c: 427-510 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[255-297] | HisKA[309-375] | HATPase_c[427-510]
  • Domain count: 3
  • Matched identifier: HKOC_1355523
  • Positioned domains: HAMP 255-297 ; HisKA 309-375 ; HATPase_c 427-510
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0211330

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_028596735
AssemblyASM2859673v1 · Contighaploid
Genome composition3 891 000 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key