Gene detail

PNX04_RS04965

Histidine kinase, Classic

Mediterraneibacter gnavus · GCF_028327405

ClassHKTypeClassicLength467 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_028327405#PNX04_RS04965Stable P2CS identifier used across views.
GenomeGCF_028327405Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1747791Run 6 · 103 sequences · id 100% · cov 80%
External referencesWP_039959544.1 · A0A2N5PQJ3 · MIST4 PNX04_RS04965RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length467 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage239 / 467 aa (51.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa467 aa
HAMP: 171-240 aa (70 aa)1HisKA: 245-304 aa (60 aa)2HATPase_c: 356-464 aa (109 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
171-240 aa · 70 aa · 15.0% of protein
Raw tokenHAMP:171:0.000000000546:240:70:69
2 HisKA#2
245-304 aa · 60 aa · 12.8% of protein
Raw tokenHisKA:245:0.000000000000359:304:60:64
3 HATPase_c#3
356-464 aa · 109 aa · 23.3% of protein
Raw tokenHATPase_c:356:7.92e-31:464:109:109
  • Raw architecture: HAMP:171:0.000000000546:240:70:69#HisKA:245:0.000000000000359:304:60:64#HATPase_c:356:7.92e-31:464:109:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_028327405::NZ_JAQMLH010000004.1::G00034
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span158384-160508Genomic interval covered by the local TCS group.
Identifiers
Old locus tagPNX04_04965RefSeq proteinWP_039959544.1
Context group IDGCF_028327405::NZ_JAQMLH010000004.1::G00034
Context members
PNX04_RS04960PNX04_RS04965
Partner locus tags
PNX04_RS04960PNX04_RS04965
Partner old locus tags
PNX04_04960PNX04_04965
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_039959544.1Primary protein accession used for annex mappings.
UniProt accessionA0A2N5PQJ3Primary UniProt accession resolved in the annex database.
UniProt IDA0A2N5PQJ3_MEDGNDisplay identifier provided by UniProt.
GO / PubMed3 / 2Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagPNX04_RS04965Primary locus identifier stored in the genes table.
Old locus tagPNX04_04965Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAQMLH010000004.1Sequence record reported by the local genomic context database.
Genomic interval159 105-160 508 nt1 404 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span158 384-160 508 ntGCF_028327405::NZ_JAQMLH010000004.1::G00034

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_028327405::NZ_JAQMLH010000004.1::G00034

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAQMLH010000004.1All displayed genes belong to this local TCS context.
Neighborhood span158 384-160 508 nt2 125 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
158 384 nt160 508 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

PNX04_RS04960GCF_028327405#PNX04_RS04960
RROmpR

158 384-159 085 nt · Forward (+)

Old locus PNX04_04960RefSeq WP_004842022.1
PNX04_RS04965GCF_028327405#PNX04_RS04965
HKClassicCurrent focus

159 105-160 508 nt · Forward (+)

Old locus PNX04_04965RefSeq WP_039959544.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1747791Run 6 · HK · 103 sequences
Representative sequenceGCF_000169475#RUMGNA_RS05705Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1747791

Simplified PFAM architecture for HKOC_1747791

PFAM domain coverage: 215 / 467 aa (46.0%)

1 aa467 aa
HAMP: 195-239 aaHAMPHisKA: 246-307 aaHisKAHATPase_c: 357-464 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[195-239] | HisKA[246-307] | HATPase_c[357-464]
  • Domain count: 3
  • Matched identifier: HKOC_1747791
  • Positioned domains: HAMP 195-239 ; HisKA 246-307 ; HATPase_c 357-464
Cluster members and taxonomy
Visualization

Representative gene: GCF_000169475#RUMGNA_RS05705

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 038 · GCF_028327405
AssemblyASM2832740v1 · Scaffoldhaploid
Genome composition3 825 911 bp · 42,0% GCMediterraneibacter gnavus
Signal transduction countsGenes 91 · HK 43 · RR 47CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key