Gene detail

O8D18_RS12540

Histidine kinase, Classic

Mediterraneibacter gnavus · GCF_027495705

ClassHKTypeClassicLength475 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_027495705#O8D18_RS12540Stable P2CS identifier used across views.
GenomeGCF_027495705Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1670005Run 6 · 4 sequences · id 100% · cov 80%
External referencesWP_269762954.1 · A0A9X3KCK1 · MIST4 O8D18_RS12540RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length475 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage243 / 475 aa (51.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa475 aa
HAMP: 162-239 aa (78 aa)1HisKA: 250-308 aa (59 aa)2HATPase_c: 365-470 aa (106 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
162-239 aa · 78 aa · 16.4% of protein
Raw tokenHAMP:162:0.00000000000968:239:78:69
2 HisKA#2
250-308 aa · 59 aa · 12.4% of protein
Raw tokenHisKA:250:0.000000128:308:59:64
3 HATPase_c#3
365-470 aa · 106 aa · 22.3% of protein
Raw tokenHATPase_c:365:3.85e-24:470:106:109
  • Raw architecture: HAMP:162:0.00000000000968:239:78:69#HisKA:250:0.000000128:308:59:64#HATPase_c:365:3.85e-24:470:106:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_027495705::NZ_JAPZED010000015.1::G00041
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span39667-41799Genomic interval covered by the local TCS group.
Identifiers
Old locus tagO8D18_12540RefSeq proteinWP_269762954.1
Context group IDGCF_027495705::NZ_JAPZED010000015.1::G00041
Context members
O8D18_RS12540O8D18_RS12545
Partner locus tags
O8D18_RS12540O8D18_RS12545
Partner old locus tags
O8D18_12540O8D18_12545
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_269762954.1Primary protein accession used for annex mappings.
UniProt accessionA0A9X3KCK1Primary UniProt accession resolved in the annex database.
UniProt IDA0A9X3KCK1_MEDGNDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagO8D18_RS12540Primary locus identifier stored in the genes table.
Old locus tagO8D18_12540Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAPZED010000015.1Sequence record reported by the local genomic context database.
Genomic interval39 667-41 094 nt1 428 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span39 667-41 799 ntGCF_027495705::NZ_JAPZED010000015.1::G00041

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_027495705::NZ_JAPZED010000015.1::G00041

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAPZED010000015.1All displayed genes belong to this local TCS context.
Neighborhood span39 667-41 799 nt2 133 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
39 667 nt41 799 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

O8D18_RS12540GCF_027495705#O8D18_RS12540
HKClassicCurrent focus

39 667-41 094 nt · Reverse (-)

Old locus O8D18_12540RefSeq WP_269762954.1
O8D18_RS12545GCF_027495705#O8D18_RS12545
RROmpR

41 107-41 799 nt · Reverse (-)

Old locus O8D18_12545RefSeq WP_269762953.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1670005Run 6 · HK · 4 sequences
Representative sequenceGCF_027495645#O8D19_RS11815Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1670005

Simplified PFAM architecture for HKOC_1670005

PFAM domain coverage: 216 / 475 aa (45.5%)

1 aa475 aa
HAMP: 188-238 aaHAMPHisKA: 251-309 aaHisKAHATPase_c: 365-470 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[188-238] | HisKA[251-309] | HATPase_c[365-470]
  • Domain count: 3
  • Matched identifier: HKOC_1670005
  • Positioned domains: HAMP 188-238 ; HisKA 251-309 ; HATPase_c 365-470
Cluster members and taxonomy
Visualization

Representative gene: GCF_027495645#O8D19_RS11815

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 038 · GCF_027495705
AssemblyASM2749570v1 · Contighaploid
Genome composition3 147 935 bp · 42,5% GCMediterraneibacter gnavus
Signal transduction countsGenes 90 · HK 44 · RR 45CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key