1 HAMP#1
288-357 aa · 70 aa · 12.0% of protein
Raw token
HAMP:288:0.0000000022:357:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
O8D18_RS07150
Histidine kinase, Classic
Mediterraneibacter gnavus · GCF_027495705
ClassHKTypeClassicLength582 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_027495705#O8D18_RS07150Stable P2CS identifier used across views.
GenomeGCF_027495705Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length582 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 582 aa (43.1%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa582 aa
Domain-by-domain annotation3 items
2 His_kinase#2
372-452 aa · 81 aa · 13.9% of protein
Raw token
His_kinase:372:3.43e-22:452:81:803 HATPase_c#3
475-574 aa · 100 aa · 17.2% of protein
Raw token
HATPase_c:475:0.0000000000000614:574:105:109- Raw architecture: HAMP:288:0.0000000022:357:70:69#His_kinase:372:3.43e-22:452:81:80#HATPase_c:475:0.0000000000000614:574:105:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_027495705::NZ_JAPZED010000005.1::G00020
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span187980-190786Genomic interval covered by the local TCS group.
Identifiers
Old locus tagO8D18_07150RefSeq proteinWP_195678466.1
Context group ID
GCF_027495705::NZ_JAPZED010000005.1::G00020Context members
O8D18_RS07150O8D18_RS07155
Partner locus tags
O8D18_RS07150O8D18_RS07155
Partner old locus tags
O8D18_07150O8D18_07155
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_195678466.1Primary protein accession used for annex mappings.
UniProt accessionA0A9X3HIM9Primary UniProt accession resolved in the annex database.
UniProt IDA0A9X3HIM9_MEDGNDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagO8D18_RS07150Primary locus identifier stored in the genes table.
Old locus tagO8D18_07150Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAPZED010000005.1Sequence record reported by the local genomic context database.
Genomic interval187 980-189 728 nt1 749 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span187 980-190 786 ntGCF_027495705::NZ_JAPZED010000005.1::G00020
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_027495705::NZ_JAPZED010000005.1::G00020Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAPZED010000005.1All displayed genes belong to this local TCS context.
Neighborhood span187 980-190 786 nt2 807 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
187 980 nt190 786 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
O8D18_RS07150GCF_027495705#O8D18_RS07150
HKClassicCurrent focus
187 980-189 728 nt · Forward (+)
O8D18_RS07155GCF_027495705#O8D18_RS07155
RRunclassified
189 716-190 786 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_015561395#I2V19_RS09725Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1154011
Simplified PFAM architecture for HKOC_1154011
PFAM domain coverage: 182 / 582 aa (31.3%)
1 aa582 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[372-451] | HATPase_c[472-573]
- Domain count: 2
- Matched identifier: HKOC_1154011
- Positioned domains: His_kinase 372-451 ; HATPase_c 472-573
Cluster members and taxonomy
Representative gene: GCF_015561395#I2V19_RS09725
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 33 038 · GCF_027495705
AssemblyASM2749570v1 · Contighaploid
Genome composition3 147 935 bp · 42,5% GCMediterraneibacter gnavus
Signal transduction countsGenes 90 · HK 44 · RR 45CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter
Related genes
Preview from the same derived genome key