Gene detail

OSC42_RS08000

Histidine kinase, Classic

Clostridioides difficile · GCF_026337685

ClassHKTypeClassicLength467 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_026337685#OSC42_RS08000Stable P2CS identifier used across views.
GenomeGCF_026337685Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1748401Run 6 · 50 sequences · id 100% · cov 80%
External referencesWP_021421560.1 · MIST4 OSC42_RS08000RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length467 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage242 / 467 aa (51.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa467 aa
HAMP: 166-232 aa (67 aa)1HisKA: 245-312 aa (68 aa)2HATPase_c: 359-465 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
166-232 aa · 67 aa · 14.3% of protein
Raw tokenHAMP:166:0.0000038:232:69:69
2 HisKA#2
245-312 aa · 68 aa · 14.6% of protein
Raw tokenHisKA:245:0.0000000000000118:312:68:64
3 HATPase_c#3
359-465 aa · 107 aa · 22.9% of protein
Raw tokenHATPase_c:359:9.8e-27:465:108:109
  • Raw architecture: HAMP:166:0.0000038:232:69:69#HisKA:245:0.0000000000000118:312:68:64#HATPase_c:359:9.8e-27:465:108:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_026337685::NZ_JAPKLZ010000029.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span73011-75143Genomic interval covered by the local TCS group.
Identifiers
Old locus tagOSC42_08020RefSeq proteinWP_021421560.1
Context group IDGCF_026337685::NZ_JAPKLZ010000029.1::G00003
Context members
OSC42_RS07995OSC42_RS08000
Partner locus tags
OSC42_RS07995OSC42_RS08000
Partner old locus tags
OSC42_08015OSC42_08020
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021421560.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagOSC42_RS08000Primary locus identifier stored in the genes table.
Old locus tagOSC42_08020Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAPKLZ010000029.1Sequence record reported by the local genomic context database.
Genomic interval73 740-75 143 nt1 404 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span73 011-75 143 ntGCF_026337685::NZ_JAPKLZ010000029.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_026337685::NZ_JAPKLZ010000029.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAPKLZ010000029.1All displayed genes belong to this local TCS context.
Neighborhood span73 011-75 143 nt2 133 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
73 011 nt75 143 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

OSC42_RS07995GCF_026337685#OSC42_RS07995
RROmpR

73 011-73 736 nt · Forward (+)

Old locus OSC42_08015RefSeq WP_004454491.1
OSC42_RS08000GCF_026337685#OSC42_RS08000
HKClassicCurrent focus

73 740-75 143 nt · Forward (+)

Old locus OSC42_08020RefSeq WP_021421560.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1748401Run 6 · HK · 50 sequences
Representative sequenceGCF_000451745#QSK_RS08640Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1748401

Simplified PFAM architecture for HKOC_1748401

PFAM domain coverage: 172 / 467 aa (36.8%)

1 aa467 aa
HisKA: 245-309 aaHisKAHATPase_c: 359-465 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-309] | HATPase_c[359-465]
  • Domain count: 2
  • Matched identifier: HKOC_1748401
  • Positioned domains: HisKA 245-309 ; HATPase_c 359-465
Cluster members and taxonomy
Visualization

Representative gene: GCF_000451745#QSK_RS08640

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_026337685
AssemblyASM2633768v1 · Contighaploid
Genome composition4 152 533 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 50 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key