Gene detail

OGM24_RS02740

Histidine kinase, Classic

Clostridioides difficile · GCF_025758245

ClassHKTypeClassicLength474 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_025758245#OGM24_RS02740Stable P2CS identifier used across views.
GenomeGCF_025758245Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1674775Run 6 · 28 sequences · id 100% · cov 80%
External referencesWP_009892645.1 · A0AB74R864 · MIST4 OGM24_RS02740RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length474 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 474 aa (53.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for OGM24_RS02740
Domain-by-domain annotation3 items
1 HAMP#1
161-238 aa · 78 aa · 16.5% of protein
Raw tokenHAMP:161:0.0000000101:238:78:69
2 HisKA#2
250-315 aa · 66 aa · 13.9% of protein
Raw tokenHisKA:250:0.00000000156:315:66:64
3 HATPase_c#3
365-471 aa · 107 aa · 22.6% of protein
Raw tokenHATPase_c:365:2.27e-26:471:107:109
  • Raw architecture: HAMP:161:0.0000000101:238:78:69#HisKA:250:0.00000000156:315:66:64#HATPase_c:365:2.27e-26:471:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_025758245::NZ_CP107113.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span520327-522462Genomic interval covered by the local TCS group.
Identifiers
Old locus tagOGM24_02740RefSeq proteinWP_009892645.1
Context group IDGCF_025758245::NZ_CP107113.1::G00005
Context members
OGM24_RS02735OGM24_RS02740
Partner locus tags
OGM24_RS02735OGM24_RS02740
Partner old locus tags
OGM24_02735OGM24_02740
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009892645.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74R864Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74R864_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagOGM24_RS02740Primary locus identifier stored in the genes table.
Old locus tagOGM24_02740Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP107113.1Sequence record reported by the local genomic context database.
Genomic interval521 038-522 462 nt1 425 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span520 327-522 462 ntGCF_025758245::NZ_CP107113.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_025758245::NZ_CP107113.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP107113.1All displayed genes belong to this local TCS context.
Neighborhood span520 327-522 462 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
520 327 nt522 462 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

OGM24_RS02735GCF_025758245#OGM24_RS02735
RROmpR

520 327-521 019 nt · Forward (+)

Old locus OGM24_02735RefSeq WP_003434748.1
OGM24_RS02740GCF_025758245#OGM24_RS02740
HKClassicCurrent focus

521 038-522 462 nt · Forward (+)

Old locus OGM24_02740RefSeq WP_009892645.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1674775Run 6 · HK · 28 sequences
Representative sequenceGCF_000450145#QK3_RS02580Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1674775

Simplified PFAM architecture for HKOC_1674775

PFAM domain coverage: 223 / 474 aa (47.0%)

1 aa474 aa
HAMP: 188-238 aaHAMPHisKA: 251-315 aaHisKAHATPase_c: 365-471 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[188-238] | HisKA[251-315] | HATPase_c[365-471]
  • Domain count: 3
  • Matched identifier: HKOC_1674775
  • Positioned domains: HAMP 188-238 ; HisKA 251-315 ; HATPase_c 365-471
Cluster members and taxonomy
Visualization

Representative gene: GCF_000450145#QK3_RS02580

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_025758245
AssemblyASM2575824v1 · Complete Genomehaploid
Genome composition4 204 257 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 107 · HK 51 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key