Gene detail

H3U45_RS16290

Histidine kinase, Classic

Clostridioides difficile · GCF_025533495

ClassHKTypeClassicLength305 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_025533495#H3U45_RS16290Stable P2CS identifier used across views.
GenomeGCF_025533495Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2882042Run 6 · 98 sequences · id 100% · cov 80%
External referencesWP_016729487.1 · MIST4 H3U45_RS16290RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length305 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage172 / 305 aa (56.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa305 aa
HisKA: 87-150 aa (64 aa)1HATPase_c: 197-304 aa (108 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
87-150 aa · 64 aa · 21.0% of protein
Raw tokenHisKA:87:0.0000000518:150:64:64
2 HATPase_c#2
197-304 aa · 108 aa · 35.4% of protein
Raw tokenHATPase_c:197:2.4e-27:304:108:109
  • Raw architecture: HisKA:87:0.0000000518:150:64:64#HATPase_c:197:2.4e-27:304:108:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_025533495::NZ_JACFWJ010000014.1::G00007
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span6620-8238Genomic interval covered by the local TCS group.
Identifiers
Old locus tagH3U45_16255RefSeq proteinWP_016729487.1
Context group IDGCF_025533495::NZ_JACFWJ010000014.1::G00007
Context members
H3U45_RS16285H3U45_RS16290
Partner locus tags
H3U45_RS16285H3U45_RS16290
Partner old locus tags
H3U45_16250H3U45_16255
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_016729487.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagH3U45_RS16290Primary locus identifier stored in the genes table.
Old locus tagH3U45_16255Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JACFWJ010000014.1Sequence record reported by the local genomic context database.
Genomic interval7 321-8 238 nt918 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span6 620-8 238 ntGCF_025533495::NZ_JACFWJ010000014.1::G00007

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_025533495::NZ_JACFWJ010000014.1::G00007

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JACFWJ010000014.1All displayed genes belong to this local TCS context.
Neighborhood span6 620-8 238 nt1 619 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
6 620 nt8 238 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

H3U45_RS16285GCF_025533495#H3U45_RS16285
RROmpR

6 620-7 318 nt · Forward (+)

Old locus H3U45_16250RefSeq WP_002347245.1
H3U45_RS16290GCF_025533495#H3U45_RS16290
HKClassicCurrent focus

7 321-8 238 nt · Forward (+)

Old locus H3U45_16255RefSeq WP_016729487.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2882042Run 6 · HK · 98 sequences
Representative sequenceGCF_000242355#MUI_RS0116830Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2882042

Simplified PFAM architecture for HKOC_2882042

PFAM domain coverage: 171 / 305 aa (56.1%)

1 aa305 aa
HisKA: 87-150 aaHisKAHATPase_c: 197-303 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[87-150] | HATPase_c[197-303]
  • Domain count: 2
  • Matched identifier: HKOC_2882042
  • Positioned domains: HisKA 87-150 ; HATPase_c 197-303
Cluster members and taxonomy
Visualization

Representative gene: GCF_000242355#MUI_RS0116830

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_025533495
AssemblyASM2553349v1 · Scaffoldhaploid
Genome composition4 098 742 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 49 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key