1 HAMP#1
142-211 aa · 70 aa · 15.3% of protein
Raw token
HAMP:142:0.00000000000773:211:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
H3U27_RS16970
Histidine kinase, Classic
Clostridioides difficile · GCF_025533155
ClassHKTypeClassicLength457 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_025533155#H3U27_RS16970Stable P2CS identifier used across views.
GenomeGCF_025533155Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length457 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage239 / 457 aa (52.3%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa457 aa
Domain-by-domain annotation3 items
2 HisKA#2
236-300 aa · 65 aa · 14.2% of protein
Raw token
HisKA:236:0.000000000023:300:65:643 HATPase_c#3
346-449 aa · 104 aa · 22.8% of protein
Raw token
HATPase_c:346:7.7e-19:449:108:109- Raw architecture: HAMP:142:0.00000000000773:211:70:69#HisKA:236:0.000000000023:300:65:64#HATPase_c:346:7.7e-19:449:108:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_025533155::NZ_JACFVS010000016.1::G00016
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span91150-93184Genomic interval covered by the local TCS group.
Identifiers
Old locus tagH3U27_16900RefSeq proteinWP_226855677.1
Context group ID
GCF_025533155::NZ_JACFVS010000016.1::G00016Context members
H3U27_RS16965H3U27_RS16970
Partner locus tags
H3U27_RS16965H3U27_RS16970
Partner old locus tags
H3U27_16895H3U27_16900
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_226855677.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagH3U27_RS16970Primary locus identifier stored in the genes table.
Old locus tagH3U27_16900Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JACFVS010000016.1Sequence record reported by the local genomic context database.
Genomic interval91 811-93 184 nt1 374 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span91 150-93 184 ntGCF_025533155::NZ_JACFVS010000016.1::G00016
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_025533155::NZ_JACFVS010000016.1::G00016Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JACFVS010000016.1All displayed genes belong to this local TCS context.
Neighborhood span91 150-93 184 nt2 035 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
91 150 nt93 184 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
H3U27_RS16965GCF_025533155#H3U27_RS16965
RROmpR
91 150-91 821 nt · Forward (+)
H3U27_RS16970GCF_025533155#H3U27_RS16970
HKClassicCurrent focus
91 811-93 184 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000322425#OM9_RS05455Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1873829
Simplified PFAM architecture for HKOC_1873829
PFAM domain coverage: 217 / 457 aa (47.5%)
1 aa457 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[161-210] | HisKA[237-300] | HATPase_c[347-449]
- Domain count: 3
- Matched identifier: HKOC_1873829
- Positioned domains: HAMP 161-210 ; HisKA 237-300 ; HATPase_c 347-449
Cluster members and taxonomy
Representative gene: GCF_000322425#OM9_RS05455
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_025533155
AssemblyASM2553315v1 · Scaffoldhaploid
Genome composition4 139 064 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 107 · HK 51 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key