Gene detail

H3U28_RS12055

Histidine kinase, Classic

Clostridioides difficile · GCF_025533075

ClassHKTypeClassicLength453 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_025533075#H3U28_RS12055Stable P2CS identifier used across views.
GenomeGCF_025533075Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1930692Run 6 · 12 sequences · id 100% · cov 80%
External referencesWP_131034960.1 · MIST4 H3U28_RS12055RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length453 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage176 / 453 aa (38.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa453 aa
HisKA: 234-298 aa (65 aa)1HATPase_c: 343-453 aa (111 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
234-298 aa · 65 aa · 14.3% of protein
Raw tokenHisKA:234:0.00000000000000254:298:65:64
2 HATPase_c#2
343-453 aa · 111 aa · 24.5% of protein
Raw tokenHATPase_c:343:1.17e-20:453:111:109
  • Raw architecture: HisKA:234:0.00000000000000254:298:65:64#HATPase_c:343:1.17e-20:453:111:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_025533075::NZ_JACFVP010000009.1::G00057
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span13895-15906Genomic interval covered by the local TCS group.
Identifiers
Old locus tagH3U28_11985RefSeq proteinWP_131034960.1
Context group IDGCF_025533075::NZ_JACFVP010000009.1::G00057
Context members
H3U28_RS12050H3U28_RS12055
Partner locus tags
H3U28_RS12050H3U28_RS12055
Partner old locus tags
H3U28_11980H3U28_11985
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_131034960.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagH3U28_RS12055Primary locus identifier stored in the genes table.
Old locus tagH3U28_11985Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JACFVP010000009.1Sequence record reported by the local genomic context database.
Genomic interval14 545-15 906 nt1 362 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span13 895-15 906 ntGCF_025533075::NZ_JACFVP010000009.1::G00057

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_025533075::NZ_JACFVP010000009.1::G00057

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JACFVP010000009.1All displayed genes belong to this local TCS context.
Neighborhood span13 895-15 906 nt2 012 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
13 895 nt15 906 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

H3U28_RS12050GCF_025533075#H3U28_RS12050
RROmpR

13 895-14 554 nt · Forward (+)

Old locus H3U28_11980RefSeq WP_131034959.1
H3U28_RS12055GCF_025533075#H3U28_RS12055
HKClassicCurrent focus

14 545-15 906 nt · Forward (+)

Old locus H3U28_11985RefSeq WP_131034960.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1930692Run 6 · HK · 12 sequences
Representative sequenceGCF_019052555#KTQ95_RS11285Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1930692

Simplified PFAM architecture for HKOC_1930692

PFAM domain coverage: 176 / 453 aa (38.9%)

1 aa453 aa
HisKA: 234-298 aaHisKAHATPase_c: 343-453 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[234-298] | HATPase_c[343-453]
  • Domain count: 2
  • Matched identifier: HKOC_1930692
  • Positioned domains: HisKA 234-298 ; HATPase_c 343-453
Cluster members and taxonomy
Visualization

Representative gene: GCF_019052555#KTQ95_RS11285

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_025533075
AssemblyASM2553307v1 · Scaffoldhaploid
Genome composition4 208 684 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 107 · HK 51 · RR 55CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key