Gene detail

H3U14_RS19485

Histidine kinase, Classic

Clostridioides difficile · GCF_025532975

ClassHKTypeClassicLength305 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_025532975#H3U14_RS19485Stable P2CS identifier used across views.
GenomeGCF_025532975Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2881988Run 6 · 241 sequences · id 100% · cov 80%
External referencesWP_011861096.1 · A0A4P9CFA0 · MIST4 H3U14_RS19485RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length305 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage175 / 305 aa (57.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa305 aa
HisKA: 85-150 aa (66 aa)1HATPase_c: 197-305 aa (109 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
85-150 aa · 66 aa · 21.6% of protein
Raw tokenHisKA:85:0.0000000591:150:66:64
2 HATPase_c#2
197-305 aa · 109 aa · 35.7% of protein
Raw tokenHATPase_c:197:4.48e-31:305:109:109
  • Raw architecture: HisKA:85:0.0000000591:150:66:64#HATPase_c:197:4.48e-31:305:109:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_025532975::NZ_JACFVH010000042.1::G00046
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span397-1314Genomic interval covered by the local TCS group.
Identifiers
Old locus tagH3U14_19345RefSeq proteinWP_011861096.1
Context group IDGCF_025532975::NZ_JACFVH010000042.1::G00046
Context members
H3U14_RS19485
Partner locus tags
H3U14_RS19485
Partner old locus tags
H3U14_19345
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_011861096.1Primary protein accession used for annex mappings.
UniProt accessionA0A4P9CFA0Primary UniProt accession resolved in the annex database.
UniProt IDA0A4P9CFA0_EUBMLDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagH3U14_RS19485Primary locus identifier stored in the genes table.
Old locus tagH3U14_19345Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JACFVH010000042.1Sequence record reported by the local genomic context database.
Genomic interval397-1 314 nt918 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span397-1 314 ntGCF_025532975::NZ_JACFVH010000042.1::G00046

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_025532975::NZ_JACFVH010000042.1::G00046

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JACFVH010000042.1All displayed genes belong to this local TCS context.
Neighborhood span397-1 314 nt918 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
397 nt1 314 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

H3U14_RS19485GCF_025532975#H3U14_RS19485
HKClassicCurrent focus

397-1 314 nt · Reverse (-)

Old locus H3U14_19345RefSeq WP_011861096.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2881988Run 6 · HK · 241 sequences
Representative sequenceGCF_000009205#CD630_RS06130Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2881988

Simplified PFAM architecture for HKOC_2881988

PFAM domain coverage: 172 / 305 aa (56.4%)

1 aa305 aa
HisKA: 85-148 aaHisKAHATPase_c: 197-304 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[85-148] | HATPase_c[197-304]
  • Domain count: 2
  • Matched identifier: HKOC_2881988
  • Positioned domains: HisKA 85-148 ; HATPase_c 197-304
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS06130

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_025532975
AssemblyASM2553297v1 · Contighaploid
Genome composition4 237 708 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 104 · HK 50 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key