1 HAMP#1
46-115 aa · 70 aa · 19.4% of protein
Raw token
HAMP:46:0.0000000000119:115:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
H3U14_RS19195
Histidine kinase, Classic
Clostridioides difficile · GCF_025532975
ClassHKTypeClassicLength361 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_025532975#H3U14_RS19195Stable P2CS identifier used across views.
GenomeGCF_025532975Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length361 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage239 / 361 aa (66.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa361 aa
Domain-by-domain annotation3 items
2 HisKA#2
140-204 aa · 65 aa · 18.0% of protein
Raw token
HisKA:140:0.0000000000462:204:65:643 HATPase_c#3
250-353 aa · 104 aa · 28.8% of protein
Raw token
HATPase_c:250:4.2e-19:353:108:109- Raw architecture: HAMP:46:0.0000000000119:115:70:69#HisKA:140:0.0000000000462:204:65:64#HATPase_c:250:4.2e-19:353:108:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_025532975::NZ_JACFVH010000030.1::G00038
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span6591-8625Genomic interval covered by the local TCS group.
Identifiers
Old locus tagH3U14_19060RefSeq proteinWP_262466934.1
Context group ID
GCF_025532975::NZ_JACFVH010000030.1::G00038Context members
H3U14_RS19195H3U14_RS19200
Partner locus tags
H3U14_RS19195H3U14_RS19200
Partner old locus tags
H3U14_19060H3U14_19065
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_262466934.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagH3U14_RS19195Primary locus identifier stored in the genes table.
Old locus tagH3U14_19060Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JACFVH010000030.1Sequence record reported by the local genomic context database.
Genomic interval6 591-7 676 nt1 086 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span6 591-8 625 ntGCF_025532975::NZ_JACFVH010000030.1::G00038
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_025532975::NZ_JACFVH010000030.1::G00038Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JACFVH010000030.1All displayed genes belong to this local TCS context.
Neighborhood span6 591-8 625 nt2 035 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
6 591 nt8 625 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
H3U14_RS19195GCF_025532975#H3U14_RS19195
HKClassicCurrent focus
6 591-7 676 nt · Reverse (-)
H3U14_RS19200GCF_025532975#H3U14_RS19200
RROmpR
7 954-8 625 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_025532975#H3U14_RS19195The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2744290
Simplified PFAM architecture for HKOC_2744290
PFAM domain coverage: 217 / 361 aa (60.1%)
1 aa361 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[65-114] | HisKA[141-204] | HATPase_c[251-353]
- Domain count: 3
- Matched identifier: HKOC_2744290
- Positioned domains: HAMP 65-114 ; HisKA 141-204 ; HATPase_c 251-353
Cluster members and taxonomy
Representative gene: GCF_025532975#H3U14_RS19195
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_025532975
AssemblyASM2553297v1 · Contighaploid
Genome composition4 237 708 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 104 · HK 50 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key