Gene detail

H3U01_RS04495

Histidine kinase, Classic

Clostridioides difficile · GCF_025532815

ClassHKTypeClassicLength468 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_025532815#H3U01_RS04495Stable P2CS identifier used across views.
GenomeGCF_025532815Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1737789Run 6 · 57 sequences · id 100% · cov 80%
External referencesWP_016728651.1 · MIST4 H3U01_RS04495RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length468 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage175 / 468 aa (37.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa468 aa
HisKA: 245-309 aa (65 aa)1HATPase_c: 357-466 aa (110 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
245-309 aa · 65 aa · 13.9% of protein
Raw tokenHisKA:245:0.00000000000187:309:65:64
2 HATPase_c#2
357-466 aa · 110 aa · 23.5% of protein
Raw tokenHATPase_c:357:5.87e-18:466:110:109
  • Raw architecture: HisKA:245:0.00000000000187:309:65:64#HATPase_c:357:5.87e-18:466:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_025532815::NZ_JACFUZ010000002.1::G00025
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span276751-278909Genomic interval covered by the local TCS group.
Identifiers
Old locus tagH3U01_04485RefSeq proteinWP_016728651.1
Context group IDGCF_025532815::NZ_JACFUZ010000002.1::G00025
Context members
H3U01_RS04490H3U01_RS04495
Partner locus tags
H3U01_RS04490H3U01_RS04495
Partner old locus tags
H3U01_04480H3U01_04485
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_016728651.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagH3U01_RS04495Primary locus identifier stored in the genes table.
Old locus tagH3U01_04485Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JACFUZ010000002.1Sequence record reported by the local genomic context database.
Genomic interval277 503-278 909 nt1 407 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span276 751-278 909 ntGCF_025532815::NZ_JACFUZ010000002.1::G00025

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_025532815::NZ_JACFUZ010000002.1::G00025

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JACFUZ010000002.1All displayed genes belong to this local TCS context.
Neighborhood span276 751-278 909 nt2 159 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
276 751 nt278 909 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

H3U01_RS04490GCF_025532815#H3U01_RS04490
RROmpR

276 751-277 458 nt · Forward (+)

Old locus H3U01_04480RefSeq WP_016728652.1
H3U01_RS04495GCF_025532815#H3U01_RS04495
HKClassicCurrent focus

277 503-278 909 nt · Forward (+)

Old locus H3U01_04485RefSeq WP_016728651.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1737789Run 6 · HK · 57 sequences
Representative sequenceGCF_000242355#MUI_RS0103550Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1737789

Simplified PFAM architecture for HKOC_1737789

PFAM domain coverage: 175 / 468 aa (37.4%)

1 aa468 aa
HisKA: 245-310 aaHisKAHATPase_c: 358-466 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-310] | HATPase_c[358-466]
  • Domain count: 2
  • Matched identifier: HKOC_1737789
  • Positioned domains: HisKA 245-310 ; HATPase_c 358-466
Cluster members and taxonomy
Visualization

Representative gene: GCF_000242355#MUI_RS0103550

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_025532815
AssemblyASM2553281v1 · Scaffoldhaploid
Genome composition4 109 934 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 48 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key