Gene detail

H3U05_RS18775

Histidine kinase, Classic

Clostridioides difficile · GCF_025532755

ClassHKTypeClassicLength265 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_025532755#H3U05_RS18775Stable P2CS identifier used across views.
GenomeGCF_025532755Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2910172Run 6 · 56 sequences · id 100% · cov 80%
External referencesWP_231299186.1 · MIST4 H3U05_RS18775RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length265 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage169 / 265 aa (63.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa265 aa
HisKA: 46-109 aa (64 aa)1HATPase_c: 156-260 aa (105 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
46-109 aa · 64 aa · 24.2% of protein
Raw tokenHisKA:46:0.00000000000329:109:64:64
2 HATPase_c#2
156-260 aa · 105 aa · 39.6% of protein
Raw tokenHATPase_c:156:4.74e-28:260:105:109
  • Raw architecture: HisKA:46:0.00000000000329:109:64:64#HATPase_c:156:4.74e-28:260:105:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_025532755::NZ_JACFUY010000023.1::G00026
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span8054-9657Genomic interval covered by the local TCS group.
Identifiers
Old locus tagH3U05_18685RefSeq proteinWP_231299186.1
Context group IDGCF_025532755::NZ_JACFUY010000023.1::G00026
Context members
H3U05_RS18775H3U05_RS18780
Partner locus tags
H3U05_RS18775H3U05_RS18780
Partner old locus tags
H3U05_18685H3U05_18690
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_231299186.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagH3U05_RS18775Primary locus identifier stored in the genes table.
Old locus tagH3U05_18685Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JACFUY010000023.1Sequence record reported by the local genomic context database.
Genomic interval8 054-8 851 nt798 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span8 054-9 657 ntGCF_025532755::NZ_JACFUY010000023.1::G00026

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_025532755::NZ_JACFUY010000023.1::G00026

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JACFUY010000023.1All displayed genes belong to this local TCS context.
Neighborhood span8 054-9 657 nt1 604 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
8 054 nt9 657 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

H3U05_RS18775GCF_025532755#H3U05_RS18775
HKClassicCurrent focus

8 054-8 851 nt · Reverse (-)

Old locus H3U05_18685RefSeq WP_231299186.1
H3U05_RS18780GCF_025532755#H3U05_RS18780
RROmpR

8 965-9 657 nt · Reverse (-)

Old locus H3U05_18690RefSeq WP_011860756.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2910172Run 6 · HK · 56 sequences
Representative sequenceGCF_000009205#CD630_RS02380Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2910172

Simplified PFAM architecture for HKOC_2910172

PFAM domain coverage: 169 / 265 aa (63.8%)

1 aa265 aa
HisKA: 46-109 aaHisKAHATPase_c: 156-260 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[46-109] | HATPase_c[156-260]
  • Domain count: 2
  • Matched identifier: HKOC_2910172
  • Positioned domains: HisKA 46-109 ; HATPase_c 156-260
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS02380

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_025532755
AssemblyASM2553275v1 · Scaffoldhaploid
Genome composition4 181 737 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 109 · HK 52 · RR 57CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key