Gene detail

H3T99_RS04250

Histidine kinase, Classic

Clostridioides difficile · GCF_025532665

ClassHKTypeClassicLength689 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_025532665#H3T99_RS04250Stable P2CS identifier used across views.
GenomeGCF_025532665Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0794313Run 6 · 17 sequences · id 100% · cov 80%
External referencesWP_070113346.1 · MIST4 H3T99_RS04250RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length689 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage162 / 689 aa (23.5%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa689 aa
HisKA: 460-527 aa (68 aa)1HATPase_c: 573-666 aa (94 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
460-527 aa · 68 aa · 9.9% of protein
Raw tokenHisKA:460:0.0000000000000221:527:68:64
2 HATPase_c#2
573-666 aa · 94 aa · 13.6% of protein
Raw tokenHATPase_c:573:0.000000000000939:666:98:109
  • Raw architecture: HisKA:460:0.0000000000000221:527:68:64#HATPase_c:573:0.000000000000939:666:98:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_025532665::NZ_JACFUT010000002.1::G00034
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span314431-317388Genomic interval covered by the local TCS group.
Identifiers
Old locus tagH3T99_04260RefSeq proteinWP_070113346.1
Context group IDGCF_025532665::NZ_JACFUT010000002.1::G00034
Context members
H3T99_RS04245H3T99_RS04250
Partner locus tags
H3T99_RS04245H3T99_RS04250
Partner old locus tags
H3T99_04255H3T99_04260
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_070113346.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagH3T99_RS04250Primary locus identifier stored in the genes table.
Old locus tagH3T99_04260Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JACFUT010000002.1Sequence record reported by the local genomic context database.
Genomic interval315 319-317 388 nt2 070 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span314 431-317 388 ntGCF_025532665::NZ_JACFUT010000002.1::G00034

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_025532665::NZ_JACFUT010000002.1::G00034

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JACFUT010000002.1All displayed genes belong to this local TCS context.
Neighborhood span314 431-317 388 nt2 958 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
314 431 nt317 388 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

H3T99_RS04245GCF_025532665#H3T99_RS04245
RROmpR

314 431-315 123 nt · Forward (+)

Old locus H3T99_04255RefSeq WP_003430378.1
H3T99_RS04250GCF_025532665#H3T99_RS04250
HKClassicCurrent focus

315 319-317 388 nt · Forward (+)

Old locus H3T99_04260RefSeq WP_070113346.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0794313Run 6 · HK · 17 sequences
Representative sequenceGCF_001757605#BW28_RS16845Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0794313

Simplified PFAM architecture for HKOC_0794313

PFAM domain coverage: 160 / 689 aa (23.2%)

1 aa689 aa
HisKA: 460-527 aaHisKAHATPase_c: 574-665 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[460-527] | HATPase_c[574-665]
  • Domain count: 2
  • Matched identifier: HKOC_0794313
  • Positioned domains: HisKA 460-527 ; HATPase_c 574-665
Cluster members and taxonomy
Visualization

Representative gene: GCF_001757605#BW28_RS16845

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_025532665
AssemblyASM2553266v1 · Contighaploid
Genome composition4 108 834 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 47 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key