Gene detail

H3U00_RS10520

Histidine kinase, Classic

Clostridioides difficile · GCF_025532655

ClassHKTypeClassicLength371 aaTM0ValidatedNoCompleteYesContextpentad
Gene IDGCF_025532655#H3U00_RS10520Stable P2CS identifier used across views.
GenomeGCF_025532655Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2676374Run 6 · 66 sequences · id 100% · cov 80%
External referencesWP_021397421.1 · MIST4 H3U00_RS10520RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length371 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 371 aa (46.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa371 aa
HisKA: 148-211 aa (64 aa)1HATPase_c: 260-368 aa (109 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
148-211 aa · 64 aa · 17.3% of protein
Raw tokenHisKA:148:0.0000000000000742:211:64:64
2 HATPase_c#2
260-368 aa · 109 aa · 29.4% of protein
Raw tokenHATPase_c:260:3.91e-25:368:110:109
  • Raw architecture: HisKA:148:0.0000000000000742:211:64:64#HATPase_c:260:3.91e-25:368:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpentadGCF_025532655::NZ_JACFUP010000006.1::G00044
Group size55 locus tags listed below.
HK / RR2 / 3Counts resolved for the local TCS neighborhood.
Context span93480-99204Genomic interval covered by the local TCS group.
Identifiers
Old locus tagH3U00_10435RefSeq proteinWP_021397421.1
Context group IDGCF_025532655::NZ_JACFUP010000006.1::G00044
Context members
H3U00_RS10520H3U00_RS10525H3U00_RS10530H3U00_RS10535H3U00_RS10540
Partner locus tags
H3U00_RS10520H3U00_RS10525H3U00_RS10530H3U00_RS10535H3U00_RS10540
Partner old locus tags
H3U00_10435H3U00_10440H3U00_10445H3U00_10450H3U00_10455

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021397421.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagH3U00_RS10520Primary locus identifier stored in the genes table.
Old locus tagH3U00_10435Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JACFUP010000006.1Sequence record reported by the local genomic context database.
Genomic interval93 480-94 595 nt1 116 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span93 480-99 204 ntGCF_025532655::NZ_JACFUP010000006.1::G00044

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_025532655::NZ_JACFUP010000006.1::G00044

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpentadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JACFUP010000006.1All displayed genes belong to this local TCS context.
Neighborhood span93 480-99 204 nt5 725 nt
Members51 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
93 480 nt99 204 nt
Neighborhood gene cards

5 genes in the current local neighborhood.

H3U00_RS10520GCF_025532655#H3U00_RS10520
HKClassicCurrent focus

93 480-94 595 nt · Reverse (-)

Old locus H3U00_10435RefSeq WP_021397421.1
H3U00_RS10525GCF_025532655#H3U00_RS10525
RROmpR

94 631-95 329 nt · Reverse (-)

Old locus H3U00_10440RefSeq WP_021422705.1
H3U00_RS10530GCF_025532655#H3U00_RS10530
RROmpR

95 710-96 390 nt · Reverse (-)

Old locus H3U00_10445RefSeq WP_003432361.1
H3U00_RS10535GCF_025532655#H3U00_RS10535
HKClassic

96 440-98 455 nt · Reverse (-)

Old locus H3U00_10450RefSeq WP_021422693.1
H3U00_RS10540GCF_025532655#H3U00_RS10540
RROmpR

98 527-99 204 nt · Reverse (-)

Old locus H3U00_10455RefSeq WP_003417201.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2676374Run 6 · HK · 66 sequences
Representative sequenceGCF_000450145#QK3_RS16740Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2676374

Simplified PFAM architecture for HKOC_2676374

PFAM domain coverage: 174 / 371 aa (46.9%)

1 aa371 aa
HisKA: 149-213 aaHisKAHATPase_c: 261-369 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[149-213] | HATPase_c[261-369]
  • Domain count: 2
  • Matched identifier: HKOC_2676374
  • Positioned domains: HisKA 149-213 ; HATPase_c 261-369
Cluster members and taxonomy
Visualization

Representative gene: GCF_000450145#QK3_RS16740

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_025532655
AssemblyASM2553265v1 · Contighaploid
Genome composition4 218 379 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 108 · HK 53 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key