Gene detail

H3T74_RS04545

Histidine kinase, Classic

Clostridioides difficile · GCF_025532455

ClassHKTypeClassicLength686 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_025532455#H3T74_RS04545Stable P2CS identifier used across views.
GenomeGCF_025532455Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0802380Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_316477195.1 · MIST4 H3T74_RS04545RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length686 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage162 / 686 aa (23.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa686 aa
HisKA: 457-524 aa (68 aa)1HATPase_c: 570-663 aa (94 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
457-524 aa · 68 aa · 9.9% of protein
Raw tokenHisKA:457:0.0000000000000185:524:68:64
2 HATPase_c#2
570-663 aa · 94 aa · 13.7% of protein
Raw tokenHATPase_c:570:0.00000000000196:663:98:109
  • Raw architecture: HisKA:457:0.0000000000000185:524:68:64#HATPase_c:570:0.00000000000196:663:98:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_025532455::NZ_JACFUF010000004.1::G00030
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span22920-25868Genomic interval covered by the local TCS group.
Identifiers
Old locus tagH3T74_04490RefSeq proteinWP_316477195.1
Context group IDGCF_025532455::NZ_JACFUF010000004.1::G00030
Context members
H3T74_RS04545H3T74_RS04550
Partner locus tags
H3T74_RS04545H3T74_RS04550
Partner old locus tags
H3T74_04490H3T74_04495
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_316477195.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagH3T74_RS04545Primary locus identifier stored in the genes table.
Old locus tagH3T74_04490Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JACFUF010000004.1Sequence record reported by the local genomic context database.
Genomic interval22 920-24 980 nt2 061 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span22 920-25 868 ntGCF_025532455::NZ_JACFUF010000004.1::G00030

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_025532455::NZ_JACFUF010000004.1::G00030

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JACFUF010000004.1All displayed genes belong to this local TCS context.
Neighborhood span22 920-25 868 nt2 949 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
22 920 nt25 868 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

H3T74_RS04545GCF_025532455#H3T74_RS04545
HKClassicCurrent focus

22 920-24 980 nt · Reverse (-)

Old locus H3T74_04490RefSeq WP_316477195.1
H3T74_RS04550GCF_025532455#H3T74_RS04550
RROmpR

25 176-25 868 nt · Reverse (-)

Old locus H3T74_04495RefSeq WP_004454566.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0802380Run 6 · HK · 1 sequences
Representative sequenceGCF_025532455#H3T74_RS04545The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0802380

Simplified PFAM architecture for HKOC_0802380

PFAM domain coverage: 160 / 686 aa (23.3%)

1 aa686 aa
HisKA: 457-524 aaHisKAHATPase_c: 571-662 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[457-524] | HATPase_c[571-662]
  • Domain count: 2
  • Matched identifier: HKOC_0802380
  • Positioned domains: HisKA 457-524 ; HATPase_c 571-662
Cluster members and taxonomy
Visualization

Representative gene: GCF_025532455#H3T74_RS04545

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_025532455
AssemblyASM2553245v1 · Scaffoldhaploid
Genome composition4 293 304 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 51 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key