1 HAMP#1
156-222 aa · 67 aa · 15.2% of protein
Raw token
HAMP:156:0.000000000693:222:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
H3T74_RS04435
Histidine kinase, Classic
Clostridioides difficile · GCF_025532455
ClassHKTypeClassicLength440 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_025532455#H3T74_RS04435Stable P2CS identifier used across views.
GenomeGCF_025532455Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length440 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage218 / 440 aa (49.5%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa440 aa
Domain-by-domain annotation3 items
2 HisKA#2
233-291 aa · 59 aa · 13.4% of protein
Raw token
HisKA:233:0.000000000238:291:59:643 HATPase_c#3
348-439 aa · 92 aa · 20.9% of protein
Raw token
HATPase_c:348:0.0000000118:439:108:109- Raw architecture: HAMP:156:0.000000000693:222:70:69#HisKA:233:0.000000000238:291:59:64#HATPase_c:348:0.0000000118:439:108:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_025532455::NZ_JACFUF010000003.1::G00029
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span272627-274646Genomic interval covered by the local TCS group.
Identifiers
Old locus tagH3T74_04380RefSeq proteinWP_243161459.1
Context group ID
GCF_025532455::NZ_JACFUF010000003.1::G00029Context members
H3T74_RS04430H3T74_RS04435
Partner locus tags
H3T74_RS04430H3T74_RS04435
Partner old locus tags
H3T74_04375H3T74_04380
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_243161459.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagH3T74_RS04435Primary locus identifier stored in the genes table.
Old locus tagH3T74_04380Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JACFUF010000003.1Sequence record reported by the local genomic context database.
Genomic interval273 324-274 646 nt1 323 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span272 627-274 646 ntGCF_025532455::NZ_JACFUF010000003.1::G00029
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_025532455::NZ_JACFUF010000003.1::G00029Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JACFUF010000003.1All displayed genes belong to this local TCS context.
Neighborhood span272 627-274 646 nt2 020 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
272 627 nt274 646 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
H3T74_RS04430GCF_025532455#H3T74_RS04430
RROmpR
272 627-273 331 nt · Forward (+)
H3T74_RS04435GCF_025532455#H3T74_RS04435
HKClassicCurrent focus
273 324-274 646 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_025532455#H3T74_RS04435The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c_53 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2077588
Simplified PFAM architecture for HKOC_2077588
PFAM domain coverage: 175 / 440 aa (39.8%)
1 aa440 aa
HAMPHisKAHATPase_c_5
- Simplified architecture: HAMP + HisKA + HATPase_c_5
- Raw architecture: HAMP[177-221] | HisKA[235-291] | HATPase_c_5[364-436]
- Domain count: 3
- Matched identifier: HKOC_2077588
- Positioned domains: HAMP 177-221 ; HisKA 235-291 ; HATPase_c_5 364-436
Cluster members and taxonomy
Representative gene: GCF_025532455#H3T74_RS04435
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_025532455
AssemblyASM2553245v1 · Scaffoldhaploid
Genome composition4 293 304 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 51 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key