Gene detail

H3T49_RS16460

Histidine kinase, Classic

Clostridioides difficile · GCF_025532375

ClassHKTypeClassicLength393 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_025532375#H3T49_RS16460Stable P2CS identifier used across views.
GenomeGCF_025532375Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2503586Run 6 · 28 sequences · id 100% · cov 80%
External referencesWP_021390943.1 · MIST4 H3T49_RS16460RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length393 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage158 / 393 aa (40.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa393 aa
HisKA: 182-240 aa (59 aa)1HATPase_c: 293-391 aa (99 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
182-240 aa · 59 aa · 15.0% of protein
Raw tokenHisKA:182:0.0000000000000143:240:59:64
2 HATPase_c#2
293-391 aa · 99 aa · 25.2% of protein
Raw tokenHATPase_c:293:2.07e-18:391:100:109
  • Raw architecture: HisKA:182:0.0000000000000143:240:59:64#HATPase_c:293:2.07e-18:391:100:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_025532375::NZ_JACFUE010000016.1::G00011
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span43492-45335Genomic interval covered by the local TCS group.
Identifiers
Old locus tagH3T49_16390RefSeq proteinWP_021390943.1
Context group IDGCF_025532375::NZ_JACFUE010000016.1::G00011
Context members
H3T49_RS16460H3T49_RS16465
Partner locus tags
H3T49_RS16460H3T49_RS16465
Partner old locus tags
H3T49_16390H3T49_16395
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021390943.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagH3T49_RS16460Primary locus identifier stored in the genes table.
Old locus tagH3T49_16390Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JACFUE010000016.1Sequence record reported by the local genomic context database.
Genomic interval43 492-44 673 nt1 182 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span43 492-45 335 ntGCF_025532375::NZ_JACFUE010000016.1::G00011

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_025532375::NZ_JACFUE010000016.1::G00011

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JACFUE010000016.1All displayed genes belong to this local TCS context.
Neighborhood span43 492-45 335 nt1 844 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
43 492 nt45 335 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

H3T49_RS16460GCF_025532375#H3T49_RS16460
HKClassicCurrent focus

43 492-44 673 nt · Reverse (-)

Old locus H3T49_16390RefSeq WP_021390943.1
H3T49_RS16465GCF_025532375#H3T49_RS16465
RROmpR

44 673-45 335 nt · Reverse (-)

Old locus H3T49_16395RefSeq WP_003434705.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2503586Run 6 · HK · 28 sequences
Representative sequenceGCF_000449785#QGW_RS02340Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2503586

Simplified PFAM architecture for HKOC_2503586

PFAM domain coverage: 162 / 393 aa (41.2%)

1 aa393 aa
HisKA: 179-240 aaHisKAHATPase_c: 292-391 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[179-240] | HATPase_c[292-391]
  • Domain count: 2
  • Matched identifier: HKOC_2503586
  • Positioned domains: HisKA 179-240 ; HATPase_c 292-391
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449785#QGW_RS02340

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_025532375
AssemblyASM2553237v1 · Contighaploid
Genome composition4 135 712 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 107 · HK 51 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key