1 HisKA#1
89-152 aa · 64 aa · 20.8% of protein
Raw token
HisKA:89:0.000000000613:152:64:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
J4G22_RS06345
Histidine kinase, Classic
Clostridioides difficile · GCF_025532335
ClassHKTypeClassicLength307 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_025532335#J4G22_RS06345Stable P2CS identifier used across views.
GenomeGCF_025532335Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length307 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage172 / 307 aa (56.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa307 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
199-306 aa · 108 aa · 35.2% of protein
Raw token
HATPase_c:199:9.42e-28:306:108:109- Raw architecture: HisKA:89:0.000000000613:152:64:64#HATPase_c:199:9.42e-28:306:108:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_025532335::NZ_JAGDLY010000044.1::G00021
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span447526-449149Genomic interval covered by the local TCS group.
Identifiers
Old locus tagJ4G22_06290RefSeq proteinWP_021421429.1
Context group ID
GCF_025532335::NZ_JAGDLY010000044.1::G00021Context members
J4G22_RS06345J4G22_RS06350
Partner locus tags
J4G22_RS06345J4G22_RS06350
Partner old locus tags
J4G22_06290J4G22_06295
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021421429.1Primary protein accession used for annex mappings.
UniProt accessionA0ABV1IQL8Primary UniProt accession resolved in the annex database.
UniProt IDA0ABV1IQL8_9FIRMDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagJ4G22_RS06345Primary locus identifier stored in the genes table.
Old locus tagJ4G22_06290Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAGDLY010000044.1Sequence record reported by the local genomic context database.
Genomic interval447 526-448 449 nt924 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span447 526-449 149 ntGCF_025532335::NZ_JAGDLY010000044.1::G00021
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_025532335::NZ_JAGDLY010000044.1::G00021Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAGDLY010000044.1All displayed genes belong to this local TCS context.
Neighborhood span447 526-449 149 nt1 624 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
447 526 nt449 149 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
J4G22_RS06345GCF_025532335#J4G22_RS06345
HKClassicCurrent focus
447 526-448 449 nt · Reverse (-)
J4G22_RS06350GCF_025532335#J4G22_RS06350
RROmpR
448 451-449 149 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000451745#QSK_RS04960Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2880580
Simplified PFAM architecture for HKOC_2880580
PFAM domain coverage: 171 / 307 aa (55.7%)
1 aa307 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[89-152] | HATPase_c[200-306]
- Domain count: 2
- Matched identifier: HKOC_2880580
- Positioned domains: HisKA 89-152 ; HATPase_c 200-306
Cluster members and taxonomy
Representative gene: GCF_000451745#QSK_RS04960
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_025532335
AssemblyASM2553233v1 · Scaffoldhaploid
Genome composition4 417 807 bp · 29,5% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 49 · RR 56CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key