Gene detail

J4F51_RS04465

Histidine kinase, Classic

Clostridioides difficile · GCF_025532325

ClassHKTypeClassicLength474 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_025532325#J4F51_RS04465Stable P2CS identifier used across views.
GenomeGCF_025532325Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1674614Run 6 · 107 sequences · id 100% · cov 80%
External referencesWP_009895522.1 · MIST4 J4F51_RS04465RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length474 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 474 aa (53.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa474 aa
HAMP: 161-238 aa (78 aa)1HisKA: 250-315 aa (66 aa)2HATPase_c: 365-471 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
161-238 aa · 78 aa · 16.5% of protein
Raw tokenHAMP:161:0.0000000146:238:78:69
2 HisKA#2
250-315 aa · 66 aa · 13.9% of protein
Raw tokenHisKA:250:0.00000000217:315:66:64
3 HATPase_c#3
365-471 aa · 107 aa · 22.6% of protein
Raw tokenHATPase_c:365:2.51e-26:471:107:109
  • Raw architecture: HAMP:161:0.0000000146:238:78:69#HisKA:250:0.00000000217:315:66:64#HATPase_c:365:2.51e-26:471:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_025532325::NZ_JAGDLT010000010.1::G00010
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span181988-184123Genomic interval covered by the local TCS group.
Identifiers
Old locus tagJ4F51_04405RefSeq proteinWP_009895522.1
Context group IDGCF_025532325::NZ_JAGDLT010000010.1::G00010
Context members
J4F51_RS04460J4F51_RS04465
Partner locus tags
J4F51_RS04460J4F51_RS04465
Partner old locus tags
J4F51_04400J4F51_04405
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_009895522.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagJ4F51_RS04465Primary locus identifier stored in the genes table.
Old locus tagJ4F51_04405Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAGDLT010000010.1Sequence record reported by the local genomic context database.
Genomic interval182 699-184 123 nt1 425 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span181 988-184 123 ntGCF_025532325::NZ_JAGDLT010000010.1::G00010

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_025532325::NZ_JAGDLT010000010.1::G00010

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAGDLT010000010.1All displayed genes belong to this local TCS context.
Neighborhood span181 988-184 123 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
181 988 nt184 123 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

J4F51_RS04460GCF_025532325#J4F51_RS04460
RROmpR

181 988-182 680 nt · Forward (+)

Old locus J4F51_04400RefSeq WP_003434748.1
J4F51_RS04465GCF_025532325#J4F51_RS04465
HKClassicCurrent focus

182 699-184 123 nt · Forward (+)

Old locus J4F51_04405RefSeq WP_009895522.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1674614Run 6 · HK · 107 sequences
Representative sequenceGCF_000376285#B131_RS0101935Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1674614

Simplified PFAM architecture for HKOC_1674614

PFAM domain coverage: 223 / 474 aa (47.0%)

1 aa474 aa
HAMP: 188-238 aaHAMPHisKA: 251-315 aaHisKAHATPase_c: 365-471 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[188-238] | HisKA[251-315] | HATPase_c[365-471]
  • Domain count: 3
  • Matched identifier: HKOC_1674614
  • Positioned domains: HAMP 188-238 ; HisKA 251-315 ; HATPase_c 365-471
Cluster members and taxonomy
Visualization

Representative gene: GCF_000376285#B131_RS0101935

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_025532325
AssemblyASM2553232v1 · Scaffoldhaploid
Genome composition4 140 790 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key