Gene detail

J4G20_RS05050

Histidine kinase, Classic

Clostridioides difficile · GCF_025532285

ClassHKTypeClassicLength439 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_025532285#J4G20_RS05050Stable P2CS identifier used across views.
GenomeGCF_025532285Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2082372Run 6 · 301 sequences · id 100% · cov 80%
External referencesWP_003426189.1 · A0A9P4DAA9 · MIST4 J4G20_RS05050RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length439 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage211 / 439 aa (48.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa439 aa
HAMP: 144-211 aa (68 aa)1HisKA: 232-296 aa (65 aa)2HATPase_c: 342-419 aa (78 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
144-211 aa · 68 aa · 15.5% of protein
Raw tokenHAMP:144:0.000000232:211:68:69
2 HisKA#2
232-296 aa · 65 aa · 14.8% of protein
Raw tokenHisKA:232:0.00000519:296:65:64
3 HATPase_c#3
342-419 aa · 78 aa · 17.8% of protein
Raw tokenHATPase_c:342:0.00000572:419:90:109
  • Raw architecture: HAMP:144:0.000000232:211:68:69#HisKA:232:0.00000519:296:65:64#HATPase_c:342:0.00000572:419:90:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_025532285::NZ_JAGDLW010000011.1::G00019
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span11117-13086Genomic interval covered by the local TCS group.
Identifiers
Old locus tagJ4G20_05025RefSeq proteinWP_003426189.1
Context group IDGCF_025532285::NZ_JAGDLW010000011.1::G00019
Context members
J4G20_RS05050J4G20_RS05055
Partner locus tags
J4G20_RS05050J4G20_RS05055
Partner old locus tags
J4G20_05025J4G20_05030
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003426189.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P4DAA9Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P4DAA9_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagJ4G20_RS05050Primary locus identifier stored in the genes table.
Old locus tagJ4G20_05025Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAGDLW010000011.1Sequence record reported by the local genomic context database.
Genomic interval11 117-12 436 nt1 320 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span11 117-13 086 ntGCF_025532285::NZ_JAGDLW010000011.1::G00019

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_025532285::NZ_JAGDLW010000011.1::G00019

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAGDLW010000011.1All displayed genes belong to this local TCS context.
Neighborhood span11 117-13 086 nt1 970 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
11 117 nt13 086 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

J4G20_RS05050GCF_025532285#J4G20_RS05050
HKClassicCurrent focus

11 117-12 436 nt · Reverse (-)

Old locus J4G20_05025RefSeq WP_003426189.1
J4G20_RS05055GCF_025532285#J4G20_RS05055
RROmpR

12 433-13 086 nt · Reverse (-)

Old locus J4G20_05030RefSeq WP_074034018.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2082372Run 6 · HK · 301 sequences
Representative sequenceGCF_000210395#CDM68_RS02360Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2082372

Simplified PFAM architecture for HKOC_2082372

PFAM domain coverage: 143 / 439 aa (32.6%)

1 aa439 aa
HisKA: 233-296 aaHisKAHATPase_c: 342-420 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[233-296] | HATPase_c[342-420]
  • Domain count: 2
  • Matched identifier: HKOC_2082372
  • Positioned domains: HisKA 233-296 ; HATPase_c 342-420
Cluster members and taxonomy
Visualization

Representative gene: GCF_000210395#CDM68_RS02360

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_025532285
AssemblyASM2553228v1 · Scaffoldhaploid
Genome composition4 279 366 bp · 29,5% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 47 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key