Gene detail

J4G20_RS02140

Histidine kinase, Classic

Clostridioides difficile · GCF_025532285

ClassHKTypeClassicLength529 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_025532285#J4G20_RS02140Stable P2CS identifier used across views.
GenomeGCF_025532285Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1359835Run 6 · 106 sequences · id 100% · cov 80%
External referencesWP_022618515.1 · MIST4 J4G20_RS02140RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length529 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage153 / 529 aa (28.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa529 aa
HisKA: 308-374 aa (67 aa)1HATPase_c: 427-512 aa (86 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
308-374 aa · 67 aa · 12.7% of protein
Raw tokenHisKA:308:0.0000000000000165:374:67:64
2 HATPase_c#2
427-512 aa · 86 aa · 16.3% of protein
Raw tokenHATPase_c:427:0.0000000463:512:90:109
  • Raw architecture: HisKA:308:0.0000000000000165:374:67:64#HATPase_c:427:0.0000000463:512:90:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_025532285::NZ_JAGDLW010000004.1::G00012
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span120911-123185Genomic interval covered by the local TCS group.
Identifiers
Old locus tagJ4G20_02105RefSeq proteinWP_022618515.1
Context group IDGCF_025532285::NZ_JAGDLW010000004.1::G00012
Context members
J4G20_RS02135J4G20_RS02140
Partner locus tags
J4G20_RS02135J4G20_RS02140
Partner old locus tags
J4G20_02100J4G20_02105
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_022618515.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagJ4G20_RS02140Primary locus identifier stored in the genes table.
Old locus tagJ4G20_02105Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAGDLW010000004.1Sequence record reported by the local genomic context database.
Genomic interval121 596-123 185 nt1 590 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span120 911-123 185 ntGCF_025532285::NZ_JAGDLW010000004.1::G00012

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_025532285::NZ_JAGDLW010000004.1::G00012

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAGDLW010000004.1All displayed genes belong to this local TCS context.
Neighborhood span120 911-123 185 nt2 275 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
120 911 nt123 185 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

J4G20_RS02135GCF_025532285#J4G20_RS02135
RROmpR

120 911-121 627 nt · Forward (+)

Old locus J4G20_02100RefSeq WP_004454617.1
J4G20_RS02140GCF_025532285#J4G20_RS02140
HKClassicCurrent focus

121 596-123 185 nt · Forward (+)

Old locus J4G20_02105RefSeq WP_022618515.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1359835Run 6 · HK · 106 sequences
Representative sequenceGCF_000451745#QSK_RS11670Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1359835

Simplified PFAM architecture for HKOC_1359835

PFAM domain coverage: 191 / 529 aa (36.1%)

1 aa529 aa
HAMP: 254-294 aaHAMPHisKA: 309-374 aaHisKAHATPase_c: 426-509 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[254-294] | HisKA[309-374] | HATPase_c[426-509]
  • Domain count: 3
  • Matched identifier: HKOC_1359835
  • Positioned domains: HAMP 254-294 ; HisKA 309-374 ; HATPase_c 426-509
Cluster members and taxonomy
Visualization

Representative gene: GCF_000451745#QSK_RS11670

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_025532285
AssemblyASM2553228v1 · Scaffoldhaploid
Genome composition4 279 366 bp · 29,5% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 47 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key